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Immune Modulator

Thymulin

Also known as: Facteur Thymique Serique (FTS)

Thymulin is a zinc-dependent nonapeptide (pGlu-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asn) secreted by thymic epithelial cells, originally isolated by Bach and colleagues in the 1970s as 'facteur thymique sérique' (FTS). It is NOT the same compound as Thymalin (a Russian bovine thymus extract) or Thymosin alpha-1 (a separate 28-amino-acid thymic peptide). Thymulin is not FDA-approved; use is research/investigational only.

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Research depth

13 citations indexed for Thymulin

All research on Thymulin →

review · 2026

Targeting Leukopoiesis: Pharmacological and Biotechnological Strategies for the Treatment of Leukopenia

Leukopenia remains a major clinical challenge associated with infectious diseases, oncological therapies, autoimmune disorders, and metabolic and iatrogenic conditions.

Study · 2026

ANP32E drives lung adenocarcinoma progression via GSK3β-mediated glycolytic reprogramming

Lung adenocarcinoma (LUAD), a leading cause of cancer mortality, involves incompletely understood epigenetic-metabolic crosstalk. We identified ANP32E as a key regulator through multi-omics (TCGA, scRNA-seq) and clinical analyses, finding its overexpression correlates with poor prognosis.

review · 2025

Maternal Thymus Adaptations and Hormone Regulation During Pregnancy

The thymus is necessary for the development of T lymphocytes and central tolerance, and adaptations in the maternal thymus are required during pregnancy. In the present paper, maternal thymic cellular anatomy, T-cell development in the thymus, and related progress are reviewed.

review · 2025

Zinc Fortification and Supplementation to Reduce Diarrhea in Children: A Literature Review

Background Zinc deficiency is a major global health issue and appears to be responsible for risk of diarrhea and death, particularly in children under 5 years. This review therefore aimed to summarize the existing literature related to zinc supplementation and fortification for the prevention of diarrhea.

review · 2025

Zinc deficiency as possible link between immunosenescence and age-related diseases

As global life expectancy increases, research reveals a critical challenge in aging: the progressive deterioration of immune function, termed immunosenescence.

animal · 2024

Systemic thymulin overexpression mitigates cognitive and molecular impairments in a rat model of sporadic Alzheimer’s Disease