Thymosin Alpha-1
Also known as: Thymalfasin (trade name Zadaxin)
Thymosin Alpha-1 (Ta1) is a 28-amino-acid thymic peptide (Ac-SDAAVDTSSEITTKDLKEKKEVVEEAEN) approved as Zadaxin in 35+ countries for chronic hepatitis B/C and as an immune adjuvant. It is NOT FDA-approved in the US.
Who's worth your money for Thymosin Alpha-1
Every current seller, ranked by independent evidence — Merit Score, latest COA purity, and live $/mg (size-normalized). Prices refresh daily. Rankings are never paid.
Top Merit pick
Highest Merit Score (99) of 21 scored sellers
$63.99 · 10mg · 99.7% purity
Best value after code
$0.06/mg effective with 15% code
$0.65 · 10mg · 99.2% purity
Most tested
21 independent COAs on file
$80.00 · 10mg · 99.6% purity
Average price
$10.02/mg
Sellers
69
45-day trend
-3.5%
56 of 69 sellers have a current price· 15 stale hidden· 20 unverified hidden
Top Merit pick
🇺🇸 Glacier Aminos99✓ verified at source · 23h ago
$6.40/mg -36.1% vs avg$63.99
10mg
- 🇺🇸 Peptide Partners99
✓ verified at source · 23h ago
$9.80/mg -2.2% vs avg$98.00
10mg
- 🇺🇸 BioLongevity Labs96
✓ verified at source · 23h ago
$13.00/mg +29.8% vs avg$130
10mg
- 🇺🇸 Profound Aminos95
via Disclosed Labs · 23h ago
$7.60/mg -24.1% vs avg$76.00
10mg
- 🇺🇸 Orbitrex Peptides95
via Disclosed Labs · 23h ago
$8.00/mg -20.1% vs avg$79.99
10mg
- 🇺🇸 Licensed Peptides95
✓ verified at source · 23h ago
$71.99/mg +618.8% vs avg$360
5mg
- 🇺🇸 Forge Performance Co.94
✓ verified at source · 23h ago
$6.00/mg -40.1% vs avg$60.00
10mg
no purityBuy code MERIT · 10% off - 🇺🇸 Riptide Wellness92
via Disclosed Labs · 23h ago
$6.50/mg -35.1% vs avg$65.00
10mg
- 🇺🇸 Hydro Research Peptides91
✓ verified at source · 23h ago
$0.07/mg -99.4% vs avg$0.65
10mg
- 🇺🇸 Peptide Plugs89
✓ verified at source · 23h ago
$6.00/mg -40.1% vs avg$60.00
10mg
Prices observed from public storefronts (last 24h), normalized to $/mg. "Evidence" is Merit's 0–100 Merit Score, derived only from observable verification evidence (methodology on /about); "Purity" is the latest independent COA. Some buy links are affiliate links — Merit may earn a commission at no extra cost to you, and where a vendor offers one, the code shown gets you a discount at their checkout. Affiliate status never affects price data, ranking, or the Merit Score (full policy on /disclosure). Research use only.
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About Thymosin Alpha-1
CAS
62304-98-7
Molecular formula
C129H215N33O55
Sequence
SDAAVDTSSEITTKDLKEKKEVVEEAEN
Typical dose range
1.6 mg subcutaneous 2–3x/week (clinical standard); research protocols range 1.6–6.4 mg per dose
Half-life
~2–3 hours (subcutaneous; elimination t½ <3 h confirmed by PK study)
COAs for Thymosin Alpha-1
107 third-party tests across 24 vendors. Each card links to the full report.
For
Thymosin Alpha-1
by NG Peptide· batch TA1-05
For
Thymosin Alpha-1
by EZ Peptides· batch EZP-TA11006052026-04
For
Thymosin Alpha-1
by Verified Peptides· batch TA05260910H
For
Thymosin Alpha-1
by Skye Peptides· batch TA126-10-001
For
Thymosin Alpha-1
by Real Peptides· batch Black Cap
For
Thymosin Alpha-1
by Pepsgpt· batch P-1947064-P
For
Thymosin Alpha-1
by Riptide Wellness· batch RWTA1-10-1003
For
Thymosin alpha-1
by Ion Peptide· batch TA110-04202026
For
Thymosin Alpha-1
by Peptide Supply Co.· batch TA1004132026
For
Thymosin Alpha-1
by OROS Research· batch OR-LPTA5-326-B1
For
Thymosin
by Verified Peptides· batch cmojb57q300trkirxximley58
For
Thymosin Alpha-1
by Amino Club· batch THA0001
For
Thymosin alpha-1
by Ion Peptide· batch TA110-03232026
For
Thymosin alpha-1
by Ion Peptide· batch TA110-03232026
For
Thymosin Alpha-1
by Profound Aminos· batch cmojb89io01hzkirx1zv5axqw
For
Thymosin Alpha-1
by Verified Peptides· batch TA032608106
For
Thymosin Alpha-1
by Peptide Partners· batch TA202602
For
Thymosin alpha-1
by Peptide Partners· batch TA202602
For
Thymosin Alpha-1
by Ion Peptide· batch TA110-02122026
For
Thymosin Alpha-1
by Glacier Aminos· batch TA10GA-03
For
Thymosin Alpha-1
by Crush Research· batch CR-TAT10-0212-1
For
Thymosin Alpha-1
by Ion Peptide· batch TA110-02122026
For
Thymosin Alpha-1
by Peptide Supply Co.· batch PSCTA110001
For
Thymoген
by BioLongevity Labs· batch 44-3-46035
20 citations indexed for Thymosin Alpha-1
Study · 2026
Thymosin Alpha-1 Restores Chemotherapy-Induced Antitumor Immunity by Chaperoning a MicroRNA Ligand of TLR7 in Dendritic Cells
Chemotherapy induces cancer cell apoptosis and the release of apoptotic bodies (ABs) that are poorly immunogenic or immunosuppressive, creating a major barrier to the success of co-administered or second-line immunotherapies.
Study · 2026
A Case Report of a Multisystemic Immune-Related Adverse Event Caused by Sintilimab in Combination With Thymosin Alpha-1
To report a case of a nasopharyngeal carcinoma patient who developed multisystem immune-related adverse events (irAEs) after treatment with sintilimab (PD-1 inhibitor) in combination with thymosin alpha-1 (Tα1). The patient presents with high fever, rash, interstitial pulmonary edema, and multiple organ failure.
rct · 2026
A Prospective, Multicenter, Open-label, Single-arm Phase II Clinical Study Evaluating the Efficacy and Safety of Spatially Fractionated Radiotherapy Combined With the PraG Strategy for the Treatment of Soft Tissue Sarcoma
The primary objective of this clinical trial is to evaluate the efficacy and safety of spatially fractionated radiotherapy combined with the PraG strategy in the treatment of soft tissue sarcoma (STS). The main questions it aims to answer are: 1.
review · 2025
Aging and Thymosin Alpha-1
Aging is characterized by immune decline, mainly due to thymic involution-the age-related shrinkage of the thymus gland. This leads to reduced T-cell production, chronic inflammation, and increased susceptibility to age-related diseases.
Study · 2025
The Immunomodulatory Activity of Thymosin Alpha 1 on Tumor Cell Lines and Distinct Immune Cell Subsets
Background The immune-balancing role of thymosin alpha 1 (Tα1) is well-recognized in contexts of immune dysregulation. Within the anti-tumor context, Tα1 demonstrated to act as an immune-enhancer, with potential roles in immunotherapy-based treatments.
meta-analysis · 2025
Thymosin alpha 1 alleviates inflammation and prevents infection in patients with severe acute pancreatitis through immune regulation: a systematic review and meta-analysis
Background Immune and inflammatory disorders are part of the complex pathophysiological processes that exacerbate severe acute pancreatitis (SAP) and subsequent infection.