Thymogen
Also known as: Thymagen
Thymogen (also marketed as Thymagen) is a synthetic dipeptide, L-Glu-L-Trp (Glu-Trp), originally isolated by the Khavinson group from the calf-thymus polypeptide complex Thymalin and then synthesized. It is registered as a pharmaceutical in Russia for immunocorrection (nasal drops / IM injection). Not FDA-approved in the US; research-use only.
Who's worth your money for Thymogen
Every current seller, ranked by independent evidence — Merit Score, latest COA purity, and live $/mg (size-normalized). Prices refresh daily. Rankings are never paid.
Top Merit pick
Highest Merit Score (96) of 1 scored sellers
$79.97 · 20mg · 99.7% purity
Average price
$3.92/mg
Sellers
15
45-day trend
-30.6%
12 of 15 sellers have a current price· 9 stale hidden· 2 unverified hidden
- 🇺🇸 BioLongevity Labs96
✓ verified at source · 23h ago
$4.00/mg +1.9% vs avg$79.97
20mg
Prices observed from public storefronts (last 24h), normalized to $/mg. "Evidence" is Merit's 0–100 Merit Score, derived only from observable verification evidence (methodology on /about); "Purity" is the latest independent COA. Some buy links are affiliate links — Merit may earn a commission at no extra cost to you, and where a vendor offers one, the code shown gets you a discount at their checkout. Affiliate status never affects price data, ranking, or the Merit Score (full policy on /disclosure). Research use only.
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About Thymogen
CAS
38101-59-6
Molecular formula
C16H19N3O5
Sequence
EW
Typical dose range
100 mcg/day intramuscular (approved Russian protocol, 3–10 day course; 300–1000 mcg total per course); nasal spray 25 mcg/nostril twice daily x 10 days
Half-life
~20–30 minutes (vendor-cited estimate; no formal Western-standard PK study available)
COAs for Thymogen
6 third-party tests across 3 vendors. Each card links to the full report.
For
Thymogen
by Kimera Chems· batch KC-TYG-CLR1
For
Thymogen
by BioLongevity Labs· batch 44-3-46031
For
Thymogen
by Mile High Compounds· batch THY-025-MH-01
For
Thymogen
by Mile High Compounds· batch THY-025-MH-01
For
Thymogen
by BioLongevity Labs· batch 44-3-45952
Purity not on file
For
Thymogen
by Skye Peptides· batch TYG200080125
12 citations indexed for Thymogen
review · 2026
Targeting Leukopoiesis: Pharmacological and Biotechnological Strategies for the Treatment of Leukopenia
Leukopenia remains a major clinical challenge associated with infectious diseases, oncological therapies, autoimmune disorders, and metabolic and iatrogenic conditions.
animal · 2025
Hepatoprotective Effects of Thymogen Analogues in Hydrazine Hepatopathy in Rats
We studied the reparative and antioxidant effects of thymogen (10 and 100 μg/kg) and its modifications in equimolar doses (12 and 120 μg/kg) obtained by attaching the amino acid D-alanine (D-Ala) to the N- or C-terminus of the peptide molecule.
review · 2024
The First Reciprocal Activities of Chiral Peptide Pharmaceuticals: Thymogen and Thymodepressin, as Examples
Peptides show high promise in the targeting and intracellular delivery of next-generation biotherapeutics. The main limitation is peptides' susceptibility to proteolysis in biological systems. Numerous strategies have been developed to overcome this challenge by chemically enhancing the resistance to proteolysis.
Study · 2023
Reparative and Antioxidant Effects of New Analogues of Immunomodulator Thymogen in Experimental Model of Liver Damage
We studied the reparative and antioxidant effects of Thymogen and its new structural analogues obtained by binding amino acid D-Ala to the N- or C-end of the peptide molecule in acute toxic hepatopathy.
review · 2023
Advancement from Small Peptide Pharmaceuticals to Orally Active Piperazine-2,5-dion-Based Cyclopeptides
The oral delivery of peptide pharmaceuticals has long been a fundamental challenge in drug development. A new chemical platform was designed based on branched piperazine-2,5-diones for creating orally available biologically active peptidomimetics.
Study · 2022
Peptides Regulating Proliferative Activity and Inflammatory Pathways in the Monocyte/Macrophage THP-1 Cell Line
This study evaluates the effects of five different peptides, the Epitalon ® tetrapeptide, the Vilon ® dipeptide, the Thymogen ® dipeptide, the Thymalin ® peptide complex, and the Chonluten ® tripeptide, as regulators of inflammatory and proliferative processes in the human monocytic THP-1, which is a human leukemia mon…