For research use only. Not for human consumption. Not medical advice — consult a licensed clinician.

GLP-1 / Metabolic

Tesofensine

Also known as: NS2330

Tesofensine is a small-molecule triple monoamine reuptake inhibitor (serotonin, norepinephrine, dopamine) — NOT a peptide. Originally developed by NeuroSearch for Parkinson's and Alzheimer's disease (which it failed to benefit) and repositioned for obesity by Saniona. Not FDA-approved in the US.

Real-time market data

Pricing for Tesofensine

Live vendor pricing, normalized to $/mg so sizes compare fairly — fused with each seller's Merit trust score and latest independent COA purity. Prices refresh daily.

Independent evidence

COAs for Tesofensine

15 third-party tests across 8 vendors. Each card links to the full report.

All 15 COAs for Tesofensine →
Measured purity 97.9%–100.0% across 3 COAs
Measured purity over time
Aggregated · 3rd-party listing
97.89 %
May 2026
Freedom Diagnostics

For

Tesofensine

by Real Peptides

Aggregated · 3rd-party listing
99.98 %
Mar 2025
BioRegen · HPLC

For

Tesofensine

by BioLongevity Labs· batch cmojb7n3x01d0kirxvvxt852q

Aggregated · 3rd-party listing
99.96 %
Mar 2025
BioRegen · HPLC

For

Tesofensine

by BioLongevity Labs· batch TESO-0001

Aggregated · 3rd-party listing
Mar 2026

Purity not on file

Vanguard Laboratory

For

Tesofensine

by Glacier Aminos· batch TES05002026-01

Aggregated · 3rd-party listing
Mar 2026

Purity not on file

Vanguard Laboratory

For

Tesofensine

by Mile High Compounds· batch TSF-500-MH-02

Aggregated · 3rd-party listing
Jan 2026

Purity not on file

Freedom Diagnostics

For

Tesofensine

by MedGe Peptides· batch 25F 019

Aggregated · 3rd-party listing
Jan 2026

Purity not on file

Freedom Diagnostics

For

Tesofensine

by MedGe Peptides· batch 25E 019

Aggregated · 3rd-party listing
Nov 2025

Purity not on file

Janoshik Analytical

For

Tesofensine

by Profound Aminos· batch cmojb89ba01hxkirx3xc405y9

Aggregated · 3rd-party listing
Oct 2025

Purity not on file

Vanguard Laboratory

For

Tesofensine

by Reta One Labs· batch TES500925

Aggregated · 3rd-party listing
Oct 2025

Purity not on file

Vanguard Laboratory

For

Tesofensine

by Reta One Labs· batch TES5000925

Aggregated · 3rd-party listing

Purity not on file

Freedom Diagnostics

For

Tesofensine

by MedGe Peptides· batch 25E 019

Aggregated · 3rd-party listing

Purity not on file

Freedom Diagnostics

For

Tesofensine

by MedGe Peptides· batch 25E 019

Aggregated · 3rd-party listing

Purity not on file

Freedom Diagnostics

For

Tesofensine

by Peptide Supply Co.· batch TFE50004072026

Aggregated · 3rd-party listing

Purity not on file

Freedom Diagnostics

For

Tesofensine

by NG Peptide· batch TSC1

Aggregated · 3rd-party listing

Purity not on file

Vanguard Laboratory

For

Tesofensine

by Certified Peptides· batch 10082025

Research depth

21 citations indexed for Tesofensine

All research on Tesofensine →

rct · 2026

Ascending single-dose study of the safety, pharmacokinetics, and pharmacodynamics of CSTI-500, a novel monoamine triple reuptake inhibitor, first-in-human

Rationale Monoamine triple reuptake inhibitors (TRIs) inhibit central dopamine, norepinephrine, and serotonin transporters, restoring functional monoamine neurotransmission.

Study · 2025

Structural basis for pharmacotherapeutic action of triple reuptake inhibitors

Most first-line pharmacotherapeutic strategies for depression aim to boost serotonin and norepinephrine levels. However, 35% of patients with depression do not respond adequately to these treatments or experience adverse side effects.

animal · 2025

Sex-specific effects of appetite suppressants on stereotypy in rats

This study investigated the sex-specific effects of commonly prescribed appetite suppressants on body weight and the manifestation of motor side effects, specifically stereotypy.

animal · 2025

Sex-specific effects of appetite suppressants and stereotypy in rats

This study investigated the sex-specific effects of commonly prescribed appetite suppressants on body weight and the manifestation of motor side effects, specifically stereotypy.

review · 2025

Obesity: Clinical Impact, Pathophysiology, Complications, and Modern Innovations in Therapeutic Strategies

Obesity is a growing global health concern with widespread impacts on physical, psychological, and social well-being.

Study · 2025

Barriers, Limitations, and Experiences with Clinical Trials-Treatment in Rare Diseases with Prader-Willi Syndrome as an Example

Background/Objectives : Developing and implementing clinical trials for rare diseases is complicated by the incomplete understanding of the varied genotype and subsequent phenotypic differences of a condition, particularly when low numbers of subjects are enrolled in a study.