Synthetic fragment of Thymosin Beta-4 active site. Studied for actin sequestration, cell migration, and tissue repair. Merit Verified tracks independent COA test results for TB-500 from multiple vendors.

Which vendors sell TB-500 with independent COA testing?

42 vendors in the Merit Verified directory have independent COA evidence on file for TB-500 — 230 COAs total. COA coverage and test dates are listed on the TB-500 page at https://meritverified.org/peptides/tb-500.

How do I verify the quality of TB-500 from a vendor?

To verify TB-500 quality, look for an independent certificate of analysis (COA) from a third-party lab — not a lab the vendor owns or pays directly. The COA should state the tested compound, lot number, purity percentage (identity and concentration), and the lab's name. Cross-reference the lot number against the vendor's current stock. Merit Verified indexes COAs for TB-500 at https://meritverified.org/peptides/tb-500 so you can compare evidence across vendors before buying.

What is the regulatory status of TB-500?

TB-500 is classified as research-use only in the Merit Verified registry. In the United States, the FDA removed several peptides including BPC-157, TB-500, and GLP-1 analogues from the 503A compounding ingredient list in April 2026, restricting their use in compounded drugs for human administration. Vendors selling TB-500 for research purposes are not selling it as a drug or supplement; the legal status of purchasing for personal use varies by jurisdiction. Merit Verified does not provide legal or medical advice — confirm current regulatory status with a licensed professional.

Healing & Recovery

TB-500

Also known as: Thymosin Beta-4 fragment, TB4 fragment

Research use only · not FDA-approved

Synthetic fragment of Thymosin Beta-4 active site. Studied for actin sequestration, cell migration, and tissue repair.

Where to buy · live market data

Who's worth your money for TB-500

Every current seller, ranked by independent evidence — Merit Score, latest COA purity, and live $/mg (size-normalized). Prices refresh daily. Rankings are never paid.

Top Merit pick

🇺🇸 Glacier Aminos 99

Highest Merit Score (99) of 37 scored sellers

$5.90/mg

$58.99 · 10mg · 99.9% purity

2 COAs

Buy Code MERIT · 10% off

Best value

🇺🇸 NG Peptide 86

Lowest $/mg among scored sellers

$3.20/mg

$64.00 · 20mg · 99.9% purity

1 COA

Buy

Most tested

🇺🇸 Verified Peptides 87

57 independent COAs on file

$6.20/mg

$62.00 · 10mg · 99.0% purity

57 COAs

Buy

Average price

$6.88/mg

range $3.00–$40.00/mg

Sellers

from $29.00

45-day trend

-14%

vs 45-day avg $/mg

52 of 69 sellers have a current price· 3 stale hidden· 12 unverified hidden

	Vendor	Price	$/mg	vs avg	Purity	COAs	Merit
🇺🇸	Glacier Aminos ✓ verified at source · 10h ago	$58.99· 10mg	$5.90/mg	-14.2%	99.9%	2	99	Buy Code MERIT · 10% off
🇺🇸	Peptide Partners ✓ verified at source · 9h ago	$130· 10mg	$13.00/mg	+89%	99.8%	16	99	Buy
🇺🇸	Hydro Research Peptides ✓ verified at source · 9h ago	$65.00· 10mg	$6.50/mg	-5.5%	99.3%	4	97	Buy Code MERIT · 15% off
🇺🇸	BioLongevity Labs via Disclosed Labs · 10h ago	$165· 10mg	$16.50/mg	+139.9%	99.8%	9	96	Buy Code MERIT · 15% off
🇺🇸	Orbitrex Peptides via Disclosed Labs · 10h ago	$49.99· 10mg	$5.00/mg	-27.3%	99.5%	4	95	Buy Code Orbitrex10 · 10% off
🇺🇸	Profound Aminos via Disclosed Labs · 10h ago	$55.00· 10mg	$5.50/mg	-20%	99.2%	4	95	Buy
🇺🇸	Prime Peptides via Disclosed Labs · 10h ago	$65.00· 10mg	$6.50/mg	-5.5%	99.5%	3	95	Buy
🇺🇸	Licensed Peptides ✓ verified at source · 9h ago	$99.99· 10mg	$10.00/mg	+45.4%	99.8%	2	95	Buy Code MERIT · 5% off
🇺🇸	Forge Performance Co. ✓ verified at source · 9h ago	$40.50· 10mg	$4.05/mg	-41.1%	99.6%	3	94	Buy Code MERIT · 10% off
	Nova Peptides via Disclosed Labs · 10h ago	$59.99· 10mg	$6.00/mg	-12.8%	99.2%	1	94	Buy

Top Merit pick

🇺🇸 Glacier Aminos
✓ verified at source · 10h ago
99

$5.90/mg -14.2% vs avg

$58.99

10mg

99.9% purity 2 COAs

Buy Code MERIT · 10% off
🇺🇸 Peptide Partners
✓ verified at source · 9h ago
99

$13.00/mg +89% vs avg

$130

10mg

99.8% purity 16 COAs

Buy
🇺🇸 Hydro Research Peptides
✓ verified at source · 9h ago
97

$6.50/mg -5.5% vs avg

$65.00

10mg

99.3% purity 4 COAs

Buy Code MERIT · 15% off
🇺🇸 BioLongevity Labs
via Disclosed Labs · 10h ago
96

$16.50/mg +139.9% vs avg

$165

10mg

99.8% purity 9 COAs

Buy Code MERIT · 15% off
🇺🇸 Orbitrex Peptides
via Disclosed Labs · 10h ago
95

$5.00/mg -27.3% vs avg

$49.99

10mg

99.5% purity 4 COAs

Buy Code Orbitrex10 · 10% off
🇺🇸 Profound Aminos
via Disclosed Labs · 10h ago
95

$5.50/mg -20% vs avg

$55.00

10mg

99.2% purity 4 COAs

Buy
🇺🇸 Prime Peptides
via Disclosed Labs · 10h ago
95

$6.50/mg -5.5% vs avg

$65.00

10mg

99.5% purity 3 COAs

Buy
🇺🇸 Licensed Peptides
✓ verified at source · 9h ago
95

$10.00/mg +45.4% vs avg

$99.99

10mg

99.8% purity 2 COAs

Buy Code MERIT · 5% off
🇺🇸 Forge Performance Co.
✓ verified at source · 9h ago
94

$4.05/mg -41.1% vs avg

$40.50

10mg

99.6% purity 3 COAs

Buy Code MERIT · 10% off
Nova Peptides
via Disclosed Labs · 10h ago
94

$6.00/mg -12.8% vs avg

$59.99

10mg

99.2% purity 1 COA

Buy

Prices observed from public storefronts (last 24h), normalized to $/mg. "Evidence" is Merit's 0–100 Merit Score, derived only from observable verification evidence (methodology on /about); "Purity" is the latest independent COA. Some buy links are affiliate links — Merit may earn a commission at no extra cost to you, and where a vendor offers one, the code shown gets you a discount at their checkout. Affiliate status never affects price data, ranking, or the Merit Score (full policy on /disclosure). Research use only.

Watch TB-500

Get one email when the market actually moves — no newsletter, no noise.

Compound reference

About TB-500

CAS

885340-08-9

Molecular formula

C38H68N10O14

Sequence

LKKTETQ

Typical dose range

2–5 mg subcutaneous or intramuscular, 1–2x per week; loading phase typically 4–6 weeks

Half-life

~1–2 hours (plasma; based on equine and in vitro studies)

Common research uses

soft tissue injury recovery (research only)wound healing studies

Safety notes

WADA-prohibited (S2 class). Not FDA-approved for human therapeutic use.

Reconstitution

Reconstitute with bacteriostatic water; stable refrigerated for ~4 weeks.

Independent evidence

COAs for TB-500

230 third-party tests across 42 vendors. Each card links to the full report.

All 230 COAs for TB-500 →

Measured purity over time

TB-500

Who's worth your money for TB-500

Watch TB-500

About TB-500

COAs for TB-500

15 citations indexed for TB-500

Effects of BPC-157 and TB-500 on Achilles tendon healing in rats: A histopathological and biomechanical study

Peptide Supplements and Their Therapeutic Applications in Sports Medicine

Paper 32. Performance & Promises: A Social Media Review of Alleged Indications, Risks and Usage of “Peptides” in Musculoskeletal Health

Therapeutic peptides in gerontology: mechanisms and applications for healthy aging

Peptides in Regenerative Medicine: A Comprehensive Review of Clinical Applications in Tissue Repair and Chronic Pain Management

Unregulated Peptide Use in the Age of Biohacking: Digital Promotion, Gray-Market Access, and Emerging Public Health Risks