Synthetic fragment of Thymosin Beta-4 active site. Studied for actin sequestration, cell migration, and tissue repair. Merit Verified tracks independent COA test results for TB-500 from multiple vendors.

Which vendors sell TB-500 with independent COA testing?

43 vendors in the Merit Verified directory have independent COA evidence on file for TB-500 — 248 COAs total. COA coverage and test dates are listed on the TB-500 page at https://meritverified.org/peptides/tb-500.

How do I verify the quality of TB-500 from a vendor?

To verify TB-500 quality, look for an independent certificate of analysis (COA) from a third-party lab — not a lab the vendor owns or pays directly. The COA should state the tested compound, lot number, purity percentage (identity and concentration), and the lab's name. Cross-reference the lot number against the vendor's current stock. Merit Verified indexes COAs for TB-500 at https://meritverified.org/peptides/tb-500 so you can compare evidence across vendors before buying.

What is the regulatory status of TB-500?

TB-500 is classified as research-use only in the Merit Verified registry. In the United States, the FDA removed several peptides including BPC-157, TB-500, and GLP-1 analogues from the 503A compounding ingredient list in April 2026, restricting their use in compounded drugs for human administration. Vendors selling TB-500 for research purposes are not selling it as a drug or supplement; the legal status of purchasing for personal use varies by jurisdiction. Merit Verified does not provide legal or medical advice — confirm current regulatory status with a licensed professional.

Healing & Recovery

TB-500

Also known as: Thymosin Beta-4 fragment, TB4 fragment

Research use only · not FDA-approved

Synthetic fragment of Thymosin Beta-4 active site. Studied for actin sequestration, cell migration, and tissue repair.

Where to buy · live market data

Who's worth your money for TB-500

Every current seller, ranked by independent evidence — Merit Score, latest COA purity, and live $/mg (size-normalized). Prices refresh daily. Rankings are never paid.

Top Merit pick

🇺🇸 Glacier Aminos 99

Highest Merit Score (99) of 39 scored sellers

$5.90/mg

$58.99 · 10mg · 99.9% purity

2 COAs

Buy Code MERIT · 10% off

Best value after code

🇺🇸 Southern Aminos 82

$2.80/mg effective with 15% code

$3.30/mg

$33.00 · 10mg

no COAs yet

Buy Code MERIT · 15% off

Most tested

🇺🇸 Verified Peptides 86

60 independent COAs on file

$6.20/mg

$62.00 · 10mg · 98.8% purity

60 COAs

Buy

Average price

$7.56/mg

range $3.13–$40.00/mg

Sellers

from $31.32

45-day trend

-12.7%

vs 45-day avg $/mg

55 of 74 sellers have a current price· 1 stale hidden· 15 unverified hidden

	Vendor	Price	$/mg	vs avg	Purity	COAs	Merit
🇺🇸	Glacier Aminos ✓ verified at source · 1h ago	$58.99· 10mg	$5.90/mg	-21.9%	99.9%	2	99	Buy Code MERIT · 10% off
🇺🇸	Peptide Partners ✓ verified at source · 3d ago	$130· 10mg	$13.00/mg	+72%	99.8%	16	99	Buy
🇺🇸	Hydro Research Peptides ✓ verified at source · just now	$65.00· 10mg	$6.50/mg	-14%	99.3%	4	97	Buy Code MERIT · 15% off
🇺🇸	Prime Peptides ✓ verified at source · just now	$65.00· 10mg	$6.50/mg	-14%	99.5%	3	96	Buy
🇺🇸	BioLongevity Labs ✓ verified at source · just now	$165· 10mg	$16.50/mg	+118.3%	99.8%	9	96	Buy Code MERIT · 15% off
🇺🇸	Orbitrex Peptides via Disclosed Labs · 5d ago · stale	$49.99· 10mg	$5.00/mg	-33.8%	99.5%	4	95	Buy Code Orbitrex10 · 10% off
🇺🇸	Profound Aminos ✓ verified at source · 3d ago · stale	$33.00· 5mg	$6.60/mg	-12.7%	99.2%	4	95	Buy
🇺🇸	Licensed Peptides ✓ verified at source · just now	$99.99· 10mg	$10.00/mg	+32.3%	99.8%	2	95	Buy Code MERIT · 5% off
🇺🇸	Sunrise Bioresearch ✓ verified at source · just now	$195· 5mg	$39.00/mg	+416.1%	—	—	95	Buy
	Nova Peptides ✓ verified at source · 1h ago	$34.99· 10mg	$3.50/mg	-53.7%	99.2%	1	94	Buy

Top Merit pick

🇺🇸 Glacier Aminos
✓ verified at source · 1h ago
99

$5.90/mg -21.9% vs avg

$58.99

10mg

99.9% purity 2 COAs

Buy Code MERIT · 10% off
🇺🇸 Peptide Partners
✓ verified at source · 3d ago
99

$13.00/mg +72% vs avg

$130

10mg

99.8% purity 16 COAs

Buy
🇺🇸 Hydro Research Peptides
✓ verified at source · just now
97

$6.50/mg -14% vs avg

$65.00

10mg

99.3% purity 4 COAs

Buy Code MERIT · 15% off
🇺🇸 Prime Peptides
✓ verified at source · just now
96

$6.50/mg -14% vs avg

$65.00

10mg

99.5% purity 3 COAs

Buy
🇺🇸 BioLongevity Labs
✓ verified at source · just now
96

$16.50/mg +118.3% vs avg

$165

10mg

99.8% purity 9 COAs

Buy Code MERIT · 15% off
🇺🇸 Orbitrex Peptides
via Disclosed Labs · 5d ago · stale
95

$5.00/mg -33.8% vs avg

$49.99

10mg

99.5% purity 4 COAs

Buy Code Orbitrex10 · 10% off
🇺🇸 Profound Aminos
✓ verified at source · 3d ago · stale
95

$6.60/mg -12.7% vs avg

$33.00

5mg

99.2% purity 4 COAs

Buy
🇺🇸 Licensed Peptides
✓ verified at source · just now
95

$10.00/mg +32.3% vs avg

$99.99

10mg

99.8% purity 2 COAs

Buy Code MERIT · 5% off
🇺🇸 Sunrise Bioresearch
✓ verified at source · just now
95

$39.00/mg +416.1% vs avg

$195

5mg

no purity

Buy
Nova Peptides
✓ verified at source · 1h ago
94

$3.50/mg -53.7% vs avg

$34.99

10mg

99.2% purity 1 COA

Buy

Prices observed from public storefronts (last 24h), normalized to $/mg. "Evidence" is Merit's 0–100 Merit Score, derived only from observable verification evidence (methodology on /about); "Purity" is the latest independent COA. Some buy links are affiliate links — Merit may earn a commission at no extra cost to you, and where a vendor offers one, the code shown gets you a discount at their checkout. Affiliate status never affects price data, ranking, or the Merit Score (full policy on /disclosure). Research use only.

Watch TB-500

Get one email when the market actually moves — no newsletter, no noise.

Compound reference

About TB-500

CAS

885340-08-9

Molecular formula

C38H68N10O14

Sequence

LKKTETQ

Typical dose range

2–5 mg subcutaneous or intramuscular, 1–2x per week; loading phase typically 4–6 weeks

Half-life

~1–2 hours (plasma; based on equine and in vitro studies)

Common research uses

soft tissue injury recovery (research only)wound healing studies

Safety notes

WADA-prohibited (S2 class). Not FDA-approved for human therapeutic use.

Reconstitution

Reconstitute with bacteriostatic water; stable refrigerated for ~4 weeks.

Independent evidence

COAs for TB-500

248 third-party tests across 43 vendors. Each card links to the full report.

All 248 COAs for TB-500 →

Measured purity over time

TB-500

Who's worth your money for TB-500

Watch TB-500

About TB-500

COAs for TB-500

15 citations indexed for TB-500

Effects of BPC-157 and TB-500 on Achilles tendon healing in rats: A histopathological and biomechanical study

Peptide Supplements and Their Therapeutic Applications in Sports Medicine

Dangers of Injectable Peptides and Other Unregulated "Biohacking" Drugs

Paper 32. Performance & Promises: A Social Media Review of Alleged Indications, Risks and Usage of “Peptides” in Musculoskeletal Health

Therapeutic peptides in gerontology: mechanisms and applications for healthy aging

Case Report: Regenerative peptides for Inferior alveolar nerve injury: a narrative review with hypothesis-generating three clinical cases