For research use only. Not for human consumption. Not medical advice — consult a licensed clinician.

GLP-1 / Metabolic

Survodutide

Also known as: BI 456906

Survodutide is a dual GLP-1 / glucagon receptor agonist co-developed by Boehringer Ingelheim and Zealand Pharma. NOT FDA-approved; received FDA Breakthrough Therapy Designation in 2024 for non-cirrhotic MASH with moderate/advanced fibrosis. Phase 3 ongoing (SYNCHRONIZE in obesity/T2DM; LIVERAGE and LIVERAGE-Cirrhosis in MASH).

Real-time market data

Pricing for Survodutide

Live vendor pricing, normalized to $/mg so sizes compare fairly — fused with each seller's Merit trust score and latest independent COA purity. Prices refresh daily.

Independent evidence

COAs for Survodutide

12 third-party tests across 3 vendors. Each card links to the full report.

All 12 COAs for Survodutide →
Measured purity 99.5%–99.8% across 6 COAs
Measured purity over time
Aggregated · 3rd-party listing
99.82 %
May 2026
Freedom Diagnostics

For

Survodutide

by Real Peptides· batch Clear Cap/Purple Crimp

Aggregated · 3rd-party listing
99.76 %
Dec 2025
Janoshik Analytical · HPLC

For

Survodutide

by Skye Peptides· batch SV25-12-001

Aggregated · 3rd-party listing
99.78 %
Oct 2025
Janoshik Analytical · HPLC

For

Survodutide

by Skye Peptides· batch SV25-06-001

Aggregated · 3rd-party listing
99.78 %
Jan 2025
MZ Biolabs · HPLC

For

Survodutide

by Profound Aminos· batch 2025-01-23

Aggregated · 3rd-party listing
99.85 %
Sep 2024
MZ Biolabs · HPLC

For

Survodutide

by Hydro Research Peptides· batch 2024-08-05

Aggregated · 3rd-party listing
99.47 %
Aug 2024
Janoshik Analytical · HPLC

For

Survodutide

by Hydro Research Peptides· batch Survodutide-6028

Aggregated · 3rd-party listing
Dec 2025

Purity not on file

Janoshik Analytical

For

Survodutide

by Skye Peptides· batch SV25-12-001

Aggregated · 3rd-party listing
Dec 2025

Purity not on file

Janoshik Analytical

For

Survodutide

by Skye Peptides· batch SV25-12-001

Aggregated · 3rd-party listing
Oct 2025

Purity not on file

Janoshik Analytical

For

Survodutide

by Skye Peptides· batch SV25-06-001

Aggregated · 3rd-party listing
Oct 2025

Purity not on file

Janoshik Analytical

For

Survodutide

by Skye Peptides· batch SV25-06-001

Aggregated · 3rd-party listing
Aug 2024

Purity not on file

Janoshik Analytical

For

Survodutide

by Hydro Research Peptides· batch Survodutide-6028

Aggregated · 3rd-party listing
Aug 2024

Purity not on file

Janoshik Analytical

For

Survodutide

by Hydro Research Peptides· batch Survodutide-6028

Research depth

29 citations indexed for Survodutide

All research on Survodutide →

Study · 2026

Survodutide for the Treatment of Obesity Disease in Japanese Participants: Rationale, Design and Baseline Characteristics of the Phase 3 SYNCHRONIZE-JP Trial

Aims There is an unmet need for effective pharmacotherapy for obesity disease management in Japan. Survodutide is a novel glucagon receptor/glucagon-like peptide-1 receptor (GLP-1R) dual agonist with the potential to induce greater weight reductions than GLP-1R mono-agonists.

Study · 2026

Efficacy of pharmacotherapies in improving liver fibrosis among patients with MASLD and fibrosis stages of F1-F3: systematic review and network meta-analysis

Background Metabolism-associated steatotic liver disease (MASLD) is one of the most prevalent chronic liver diseases worldwide.

Study · 2026

Survodutide acts through circumventricular organs in the brain and activates neuronal regions associated with appetite regulation

Survodutide is a novel GCG/GLP-1 receptor (GCGR/GLP-1R) dual agonist in clinical development for people with obesity and people with metabolic dysfunction-associated steatohepatitis (MASH).

meta-analysis · 2026

Comparative Efficacy and Safety of Glucagon Receptor Agonists on Metabolic Outcomes: A Network Meta-Analysis of Randomised Controlled Trials

Introduction Glucagon receptor agonists (GRAs) are an emerging class of therapies for obesity and type 2 diabetes, demonstrating encouraging metabolic and weight-reducing effects.

Study · 2026

A review of survodutide: a new dual acting agonist

Survodutide represents an innovative approach to obesity management and metabolic-associated fatty liver disease (MAFLD). These conditions, often closely linked with type 2 diabetes (T2DM) and cardiovascular diseases, demand effective treatment strategies.

review · 2026

Acute Contractile Effects of Glucagon-like-Peptide-1 Receptor Agonists in the Human Heart

Glucagon-like-peptide-1 receptor (GLP-1R) agonists are under development as new drugs to treat type 2 diabetes, liver disease, obesity and cardiovascular diseases. Some of these drugs are solely agonists of the GLP-1R.