Sermorelin
Also known as: Geref
Sermorelin is a synthetic analog of growth hormone-releasing hormone (GHRH) consisting of the first 29 amino acids of the 44-aa native hormone — the shortest fragment that retains full biological activity. It was FDA-approved in the 1990s as Geref (EMD Serono) for diagnostic testing of pituitary GH reserve and later for pediatric idiopathic GH deficiency, but was withdrawn from the US market in 2008–2009 at the manufacturer's request for commercial reasons (not safety or efficacy). It remains on the FDA Category 1 list of bulk substances nominated for use in 503A compounding, where it is now widely prescribed off-label for adult GH insufficiency and "anti-aging" indications.
Who's worth your money for Sermorelin
Every current seller, ranked by independent evidence — Merit Score, latest COA purity, and live $/mg (size-normalized). Prices refresh daily. Rankings are never paid.
Top Merit pick
Highest Merit Score (99) of 18 scored sellers
$62.99 · 10mg · 100.0% purity
Best value after code
$0.05/mg effective with 15% code
$0.64 · 10mg
Most tested
8 independent COAs on file
$405 · 5mg · 99.0% purity
Average price
$8.75/mg
Sellers
66
45-day trend
-7.4%
56 of 66 sellers have a current price· 16 stale hidden· 22 unverified hidden
Top Merit pick
🇺🇸 Glacier Aminos99✓ verified at source · 23h ago
$6.30/mg -28% vs avg$62.99
10mg
- 🇺🇸 Orbitrex Peptides95
via Disclosed Labs · 23h ago
$5.00/mg -42.9% vs avg$49.99
10mg
- 🇺🇸 Prime Peptides95
via Disclosed Labs · 23h ago
$6.50/mg -25.7% vs avg$65.00
10mg
- 🇺🇸 Profound Aminos95
via Disclosed Labs · 23h ago
$7.60/mg -13.1% vs avg$76.00
10mg
- 🇺🇸 Licensed Peptides95
✓ verified at source · 23h ago
$80.99/mg +825.7% vs avg$405
5mg
- 🇺🇸 Ignite Peptides92
✓ verified at source · 23h ago
$10.00/mg +14.3% vs avg$50.00
5mg
- 🇺🇸 Hydro Research Peptides91
✓ verified at source · 23h ago
$0.06/mg -99.3% vs avg$0.64
10mg
- 🇺🇸 Peptide Plugs89
✓ verified at source · 23h ago
$5.50/mg -37.1% vs avg$55.00
10mg
- 🇺🇸 Peptidology89
✓ verified at source · 23h ago
$8.00/mg -8.6% vs avg$79.95
10mg
- 🇺🇸 EZ Peptides85
✓ verified at source · 23h ago
$8.80/mg +0.6% vs avg$44.00
5mg
Prices observed from public storefronts (last 24h), normalized to $/mg. "Evidence" is Merit's 0–100 Merit Score, derived only from observable verification evidence (methodology on /about); "Purity" is the latest independent COA. Some buy links are affiliate links — Merit may earn a commission at no extra cost to you, and where a vendor offers one, the code shown gets you a discount at their checkout. Affiliate status never affects price data, ranking, or the Merit Score (full policy on /disclosure). Research use only.
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About Sermorelin
CAS
86168-78-7
Molecular formula
C149H246N44O42S
Sequence
YADAIFTNSYRKVLGQLSARKLLQDIMSR
Typical dose range
200-500 mcg/day subcutaneous injection, typically administered at bedtime
Half-life
~10-20 minutes (plasma elimination half-life after subcutaneous administration)
COAs for Sermorelin
121 third-party tests across 24 vendors. Each card links to the full report.
For
Sermorelin
by Ignite Peptides· batch IP-2607-231
For
Sermorelin
by NG Peptide· batch SM10-05
For
Sermorelin
by NG Peptide· batch sm10-05
For
Sermorelin
by Crush Research· batch CR-SMLN-10MG-2605-1
For
Sermorelin
by Ion Peptide· batch SMO10-05122026
For
Sermorelin
by Profound Aminos· batch Grey Cap
For
Sermorelin
by Profound Aminos· batch Grey Cap
For
Sermorelin
by Peptide Supply Co.· batch SM1005192026
For
SERMO
by Ion Peptide· batch SMO5-05072026
For
SERMO
by Ion Peptide· batch SMO5-05072026
For
Sermorelin
by EZ Peptides· batch EZP-SER0505052026-05
For
Sermorelin
by EZ Peptides· batch EZP-SER0505052026-05
For
Sermorelin
by Ignite Peptides· batch sermor41601
For
Sermorelin
by Licensed Peptides· batch Black Cap
For
Sermorelin
by Real Peptides· batch Black Cap
For
Sermorelin
by NG Peptide· batch SM10-04
For
Sermorelin
by Pepsgpt· batch P-3758495-P
For
Sermorelin
by Reta Peptide· batch 20260409
For
Sermorelin
by OROS Research· batch OR-LPSERM5-426-B4
For
Sermorelin
by Ion Peptide· batch SERM10-04072026
For
Sermorelin
by Peptide Partners· batch SER202601
For
Sermorelin
by Ion Peptide· batch SERM10-03232026
For
Sermorelin
by Ion Peptide· batch SERM10-03232026
For
Sermorelin
by Kimera Chems· batch KC-SEM-GRN1
20 citations indexed for Sermorelin
review · 2026
The emerging landscape of performance-enhancing peptides modulating GH-IGF1 axis: bridging the gap between clinical evidence and patient self-administration
Performance-enhancing drugs (PEDs) marketed as "research compounds" include unregulated peptides intended to modulate the growth hormone-insulin-like growth factor-1 (GH-IGF-1) axis.
review · 2026
Safety and Efficacy of Approved and Unapproved Peptide Therapies for Musculoskeletal Injuries and Athletic Performance
Peptides are short chains of amino acids with a unique pharmacological niche between small-molecule drugs and large proteins. Their use in sports medicine is rapidly expanding, driven by patient demand for accelerated injury recovery and performance enhancement.
review · 2026
A new era of doping? Use of peptide and peptide-analog drugs in recreational and professional sport and bodybuilding: a critical review
The pursuit of pharmacological enhancement in sport has evolved from the widespread use of anabolic-androgenic steroids (AAS) to novel agents such as peptides and peptide analogues.
case-report · 2026
Anterior cervical osteophyte-related dysphagia in a long-term growth hormone user: a case report
Background Anterior cervical osteophytes can compress the esophagus, producing dysphagia. Although common on imaging in older adults, symptomatic osteophytic dysphagia is underdiagnosed, and the role of systemic anabolic factors in osteophyte growth is poorly characterized.
Study · 2026
Analysis of growth hormone releasing hormone and its analogs in urine using nano liquid chromatography coupled with quadrupole/orbitrap mass spectrometry
Growth hormone-releasing hormone (GHRH) and its synthetic analogs are considered performance-enhancing substances and are therefore prohibited by the World Anti-Doping Agency (WADA).
review · 2026
Injectable Peptides in Sports Medicine: A Structured Narrative Review of Evidence, Safety, and Antidoping Implications
Background Injectable peptides are increasingly promoted for musculoskeletal recovery, tissue repair, and performance enhancements; however, clinical adoption has outpaced high-quality evidence and regulatory consensus.