Sermorelin
Also known as: Geref
Sermorelin is a synthetic analog of growth hormone-releasing hormone (GHRH) consisting of the first 29 amino acids of the 44-aa native hormone — the shortest fragment that retains full biological activity. It was FDA-approved in the 1990s as Geref (EMD Serono) for diagnostic testing of pituitary GH reserve and later for pediatric idiopathic GH deficiency, but was withdrawn from the US market in 2008–2009 at the manufacturer's request for commercial reasons (not safety or efficacy). It remains on the FDA Category 1 list of bulk substances nominated for use in 503A compounding, where it is now widely prescribed off-label for adult GH insufficiency and "anti-aging" indications.
Who's worth your money for Sermorelin
Every current seller, ranked by independent evidence — Merit Score, latest COA purity, and live $/mg (size-normalized). Prices refresh daily. Rankings are never paid.
Top Merit pick
Highest Merit Score (99) of 31 scored sellers
$62.99 · 10mg · 100.0% purity
Best value
Lowest $/mg among scored sellers
$380 · 100mg · 99.5% purity
Most tested
8 independent COAs on file
$98.00 · 10mg · 99.9% purity
Average price
$8.41/mg
Sellers
55
45-day trend
-24.1%
40 of 55 sellers have a current price· 9 unverified hidden
Top Merit pick
🇺🇸 Glacier Aminos99✓ verified at source · 1h ago
$6.30/mg -25.1% vs avg$62.99
10mg
- 🇺🇸 Peptide Partners99
✓ verified at source · 3d ago
$9.80/mg +16.6% vs avg$98.00
10mg
- 🇺🇸 Hydro Research Peptides97
✓ verified at source · just now
$6.40/mg -23.9% vs avg$64.00
10mg
- 🇺🇸 Prime Peptides96
✓ verified at source · just now
$7.00/mg -16.7% vs avg$70.00
10mg
- 🇺🇸 Orbitrex Peptides95
via Disclosed Labs · 5d ago · stale
$6.00/mg -28.6% vs avg$59.99
10mg
- 🇺🇸 Profound Aminos95
✓ verified at source · 3d ago · stale
$8.00/mg -4.8% vs avg$40.00
5mg
- 🇺🇸 Sunrise Bioresearch95
✓ verified at source · just now
$41.00/mg +387.7% vs avg$205
5mg
no purity - 🇺🇸 Forge Performance Co.94
via Disclosed Labs · 5d ago · stale
$5.00/mg -40.5% vs avg$50.00
10mg
no purityBuy Code MERIT · 10% off - 🇺🇸 Peptide Crafters94
✓ verified at source · 1h ago
$5.50/mg -34.6% vs avg$55.00
10mg
- Nova Peptides94
✓ verified at source · 1h ago
$10.00/mg +18.9% vs avg$49.99
5mg
Prices observed from public storefronts (last 24h), normalized to $/mg. "Evidence" is Merit's 0–100 Merit Score, derived only from observable verification evidence (methodology on /about); "Purity" is the latest independent COA. Some buy links are affiliate links — Merit may earn a commission at no extra cost to you, and where a vendor offers one, the code shown gets you a discount at their checkout. Affiliate status never affects price data, ranking, or the Merit Score (full policy on /disclosure). Research use only.
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About Sermorelin
CAS
86168-78-7
Molecular formula
C149H246N44O42S
Sequence
YADAIFTNSYRKVLGQLSARKLLQDIMSR
Typical dose range
200-500 mcg/day subcutaneous injection, typically administered at bedtime
Half-life
~10-20 minutes (plasma elimination half-life after subcutaneous administration)
COAs for Sermorelin
161 third-party tests across 38 vendors. Each card links to the full report.
For
Sermorelin
by VoriLabs· batch SERM-M2609-B
For
Sermorelin
by Certified Peptides· batch SERM1-926
For
Sermorelin
by Velora Biolabs· batch VBL-SR10-1
For
Sermorelin 10mg
by optimasupply.is· batch OS-2026-5483
For
Sermorelin
by Ignite Peptides· batch IP-2607-231
For
Sermorelin
by NG Peptide· batch SM10-05
For
Sermorelin
by NG Peptide· batch sm10-05
For
Sermorelin
by OROS Research· batch OR-LPSERM5-626-B5
For
Sermorelin
by Crush Research· batch CR-SMLN-10MG-2605-1
For
Sermorelin
by Ion Peptide· batch SMO10-05122026
For
Sermorelin
by Modern Research Peptides· batch CGMK56226
For
Sermorelin
by Profound Aminos· batch Grey Cap
For
Sermorelin
by Peptide Crafters· batch PC-G3-SER10
For
Sermorelin
by Profound Aminos· batch Grey Cap
For
Sermorelin
by Peptide Supply Co.· batch SM1005192026
For
SERMO
by Ion Peptide· batch SMO5-05072026
For
SERMO
by Ion Peptide· batch SMO5-05072026
For
Sermorelin
by EZ Peptides· batch EZP-SER0505052026-05
For
Sermorelin
by Sports Technology Labs· batch 2026-05-15
For
Sermorelin
by EZ Peptides· batch EZP-SER0505052026-05
For
Sermorelin
by Ignite Peptides· batch sermor41601
For
Sermorelin
by Licensed Peptides· batch Black Cap
For
Sermorelin
by Real Peptides· batch Black Cap
For
Sermorelin
by Blank Peptides· batch SERM10-042026-4
20 citations indexed for Sermorelin
review · 2026
Peptides in urology and sexual medicine: clinical effectiveness, dosing, indications, and safety: a narrative review
Introduction Peptide-based therapies are increasingly used in urology and sexual medicine, although adoption is often influenced by off-label prescribing, direct-to-consumer promotion, and limited long-term safety data. We review mechanisms, clinical evidence, dosing, safety, and regulatory status of these agents.
Study · 2026
Growth hormone - releasing hormone antagonists protect endothelial corneal cells against lipopolysaccharides-induced inflammation
The corneal endothelium preserves corneal transparency by regulating water movement between the anterior chamber and the stroma. Pathological conditions may lead to progressive corneal edema due to impairment of the endothelial pump-barrier function.
Study · 2026
Cardiomyocyte-specific expression of HIF-1α mediates the cardioprotective effects of growth hormone-releasing hormone
Heart failure (HF) with preserved ejection fraction (HFpEF) carries a high mortality and remains a major therapeutic challenge. Effective targeted therapies capable of reversing HFpEF pathophysiology are urgently needed.
review · 2026
Safety and Efficacy of Approved and Unapproved Peptide Therapies for Musculoskeletal Injuries and Athletic Performance
Peptides are short chains of amino acids with a unique pharmacological niche between small-molecule drugs and large proteins. Their use in sports medicine is rapidly expanding, driven by patient demand for accelerated injury recovery and performance enhancement.
case-report · 2026
Anterior cervical osteophyte-related dysphagia in a long-term growth hormone user: a case report
Background Anterior cervical osteophytes can compress the esophagus, producing dysphagia. Although common on imaging in older adults, symptomatic osteophytic dysphagia is underdiagnosed, and the role of systemic anabolic factors in osteophyte growth is poorly characterized.
review · 2026
A new era of doping? Use of peptide and peptide-analog drugs in recreational and professional sport and bodybuilding: a critical review
The pursuit of pharmacological enhancement in sport has evolved from the widespread use of anabolic-androgenic steroids (AAS) to novel agents such as peptides and peptide analogues.