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Immune Modulator

Prostamax

Also known as: prostamaxum

Prostamax is a Khavinson-series 'peptide bioregulator' associated with the synthetic tetrapeptide Lys-Glu-Asp-Pro (KEDP), positioned as a short-peptide analog of bovine prostate extracts (in the same Russian product family as Prostatilen / Vitaprost). It is marketed on the Russian/Ukrainian grey market as a dietary peptide for prostate support; not an FDA-approved drug and not a substitute for evaluated BPH or prostatitis therapies. Research-use only in the US.

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Research depth

6 citations indexed for Prostamax

All research on Prostamax →

animal · 2017

Peptides (Epigenetic Regulators) in the Structure of Rodents with a Long and Short Lifespan

We have discovered motives of short-chain epigenetically active peptides in some proteins of long-lived African mole rat Heterocephalus glaber. These epigenetic regulators are located in the protein structure between lysine and arginine residues, thus facilitating their release in limited proteolysis.

Study · 2012

[Deheterochromatinization of the chromatin in old age induced by oligopeptide bioregulator (Lys-Glu-Asp-Pro)]

In this work is presented the data on the variability of the functional characteristics of the chromosomes in the cells exposed by oligopeptide bioregulator - Prostamax from old individuals (75-86 years).

Study · 2009

Microcalorimetric study of human blood lymphocytes culture at presence of copper, cadmium and prostamax

Research goal was study of separate and joint influence of bioregulator prostamax and Cu(II) and Cd(II) ions on the chromatin structure in situ.

animal · 2006

[The tissue-specific effect of synthetic peptides-biologic regulators in organotypic tissues culture in young and old rats]

The synthetic peptides--cardiogen, bronchogen, prostamax and pancragen were used to investigate their effect on organotypic tissue culture of explants from heart, lungs, prostatic gland and pancreas of young (3-week old) and aged (18-month old) rats.

Study · 2004

[The influence of the peptide bioregulator prostamax on heterochromatin of human lymphocytes in situ]

It was shown that chromatin contained in human lymphocytes has two stages of denaturation: with T(d)VII = 94.4 degrees C, Q(d)VII = 50.8 J/g DNA, and T(d)VIII = 105.1 degrees C Q(d)VIII = 44.9 J/g DNA.

Study · 2004

Effects of short peptides on lymphocyte chromatin in senile subjects

Effects of synthetic short peptides (Vilon, Epithalon, Livagen, Prostamax, and Cortagen) on activity of ribosome genes, parameters of common heterochromatin melting, polymorphism of structural heterochromatin (C segments) of chromosomes 1, 9, and 16, and variability of facultative heterochromatin were studied in leukoc…