PEG-MGF
Also known as: PEGylated Mechano Growth Factor
PEG-MGF is the pegylated form of Mechano Growth Factor (MGF), the distinct 24-amino-acid C-terminal E-peptide encoded by the IGF-1Ec splice variant (IGF-1Eb in rodents) that is transiently upregulated in muscle after mechanical loading or damage. MGF is related to but pharmacologically distinct from mature IGF-1 and IGF-1 LR3. Pegylation extends its half-life from minutes to several hours, and the compound is marketed as a research chemical for muscle repair protocols. It is not FDA-approved for any indication.
Who's worth your money for PEG-MGF
Every current seller, ranked by independent evidence — Merit Score, latest COA purity, and live $/mg (size-normalized). Prices refresh daily. Rankings are never paid.
Top Merit pick
Highest Merit Score (96) of 6 scored sellers
$94.97 · 5mg · 99.7% purity
Best value
Lowest $/mg among scored sellers
$34.99 · 2mg
Most tested
3 independent COAs on file
$39.00 · 2mg · 99.8% purity
Average price
$20.69/mg
Sellers
19
45-day trend
+11.3%
16 of 19 sellers have a current price· 5 stale hidden· 5 unverified hidden
Top Merit pick
🇺🇸 BioLongevity Labs96✓ verified at source · 23h ago
$18.99/mg -8.2% vs avg$94.97
5mg
- 🇺🇸 Moglabs96
via Disclosed Labs · 23h ago
$20.00/mg -3.3% vs avg$40.00
2mg
- 🇺🇸 Ion Peptide95
✓ verified at source · 23h ago
$19.50/mg -5.7% vs avg$39.00
2mg
- 🇺🇸 Peptide Tech94
✓ verified at source · 2d ago
$17.50/mg -15.4% vs avg$34.99
2mg
no purity - 🇺🇸 Simple Peptide85
✓ verified at source · 23h ago
$19.50/mg -5.7% vs avg$39.00
2mg
- Sports Technology Labs58
✓ verified at source · 23h ago
$23.50/mg +13.6% vs avg$46.99
2mg
Prices observed from public storefronts (last 24h), normalized to $/mg. "Evidence" is Merit's 0–100 Merit Score, derived only from observable verification evidence (methodology on /about); "Purity" is the latest independent COA. Some buy links are affiliate links — Merit may earn a commission at no extra cost to you, and where a vendor offers one, the code shown gets you a discount at their checkout. Affiliate status never affects price data, ranking, or the Merit Score (full policy on /disclosure). Research use only.
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About PEG-MGF
CAS
—
Molecular formula
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Sequence
YQPPSTNKNTKSQRRKGSTFEERK
Typical dose range
200–400 mcg subcutaneous, 2–3x per week
Half-life
~48–72 hours (vs. ~5–7 minutes for unmodified MGF)
COAs for PEG-MGF
13 third-party tests across 8 vendors. Each card links to the full report.
For
PEG-MGF with Trehalose
by Skye Peptides· batch PMG26-05-001
For
PEG-MGF
by BioLongevity Labs· batch QC260699
For
PEG-MGF
by Ruo Bio
For
PEG-MGF
by Ion Peptide· batch PMGF-010226
For
PEG-MGF
by Ion Peptide· batch PMGF-121325
For
PEG-MGF
by Sports Technology Labs· batch 2025-10-06
For
PEG-MGF
by Simple Peptide· batch PEGM08252025-J
For
PEG-MGF
by Ion Peptide· batch PMGF-010226
Purity not on file
For
PEG-MGF with Trehalose
by Skye Peptides· batch PMG26-05-001
Purity not on file
For
PEG-MGF with Trehalose
by Skye Peptides· batch PMG26-05-001
Purity not on file
For
PEG-MGF
by Peptidegurus· batch cmojgr60i002i9grxmefx6ikp
Purity not on file
For
PEG-MGF
by Moglabs
Purity not on file
For
PEG-MGF
by Ruo Bio
11 citations indexed for PEG-MGF
review · 2026
The emerging landscape of performance-enhancing peptides modulating GH-IGF1 axis: bridging the gap between clinical evidence and patient self-administration
Performance-enhancing drugs (PEDs) marketed as "research compounds" include unregulated peptides intended to modulate the growth hormone-insulin-like growth factor-1 (GH-IGF-1) axis.
rct · 2025
A Clinical Trial of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease
The purpose of this study is to assess the efficacy and safety of trontinemab in participants with early symptomatic Alzheimer's disease (AD) (mild cognitive impairment \[MCI\] to mild dementia due to AD).
rct · 2021
A Research Study Investigating Semaglutide in People With Early Alzheimer's Disease (EVOKE)
This study is done to find out whether the medicine, semaglutide, has a positive effect on early Alzheimer's disease. Participants will either get semaglutide or placebo (a "dummy" medicine which does not contain any study medicine) - which treatment participants get is decided by an equal chance.
Study · 2017
The Generation of Dehydroalanine Residues in Protonated Polypeptides: Ion/Ion Reactions for Introducing Selective Cleavages
We examine a gas-phase approach for converting a subset of amino acid residues in polypeptide cations to dehydroalanine (Dha). Subsequent activation of the modified polypeptide ions gives rise to specific cleavage N-terminal to the Dha residue.
rct · 2016
A Study of PEG-somatropin Injection to Treat Children of Turner Syndrome
This study aims to explore the optimal dose of pegylated recombinant human growth hormone (PEG-rhGH) injection to treat children of Turner syndrome (TS), preliminarily evaluate its safety and efficacy and provide scientific and reliable evidence for the medication dosage in Phase 3 clinical trial.
rct · 2015
Clinical Study of Pegylated Somatropin (PEG Somatropin) to Treat SGA Children With Short Stature
The study was evaluated as the optimal dose for the treatment of SGA short stature children by Pegylated Somatropin, initially evaluated its efficiency and safety for the treatment of SGA short stature children and provided scientific, reliable basis for phase III clinical trials for dose selection.