For research use only. Not for human consumption. Not medical advice — consult a licensed clinician.

Immune Modulator

NAD+

Also known as: Nicotinamide Adenine Dinucleotide

NAD+ (nicotinamide adenine dinucleotide) is a coenzyme present in all living cells, not a peptide. It is classified here alongside peptides for user convenience in the anti-aging / metabolic category. NAD+ plays a central role in cellular energy metabolism and redox reactions and is studied for its involvement in mitochondrial function, DNA-damage signaling via sirtuins and PARPs, and age-associated metabolic decline. IV NAD+ is not FDA-approved for any clinical indication; it is administered off-label through compounding pharmacies and functional-medicine clinics with limited rigorous outcome data.

Real-time market data

Pricing for NAD+

Live vendor pricing, normalized to $/mg so sizes compare fairly — fused with each seller's Merit trust score and latest independent COA purity. Prices refresh daily.

Independent evidence

COAs for NAD+

119 third-party tests across 30 vendors. Each card links to the full report.

All 119 COAs for NAD+ →
Measured purity 91.3%–100.0% across 52 COAs
Measured purity over time
Aggregated · 3rd-party listing
99.27 %
Jun 2026
ILS Labs

For

NAD+

by Crush Research· batch CR-NAD500-2605-1

Aggregated · 3rd-party listing
99.22 %
Jun 2026
ILS Labs

For

NAD+

by Crush Research· batch CR-NAD-1000MG-2605-2

Aggregated · 3rd-party listing
97.54 %
May 2026
ILS Labs

For

NAD+

by Sunrise Bioresearch· batch NAD500MAY26-01

Aggregated · 3rd-party listing
99.44 %
May 2026
ILS Labs · HPLC

For

NAD+

by Crush Research· batch CR-NJ500-0309-1

Aggregated · 3rd-party listing
99.63 %
May 2026
ILS Labs

For

NAD+

by Ion Peptide· batch NJ1000-05042026

Aggregated · 3rd-party listing
99.62 %
May 2026
ILS Labs

For

NAD+

by Ion Peptide· batch NJ500-05042026

Aggregated · 3rd-party listing
99.72 %
May 2026
MDx BioAnalytical Laboratory

For

NAD+

by BioLongevity Labs

Aggregated · 3rd-party listing
99.72 %
May 2026
MDx BioAnalytical Laboratory

For

NAD+

by BioLongevity Labs

Aggregated · 3rd-party listing
99.12 %
Apr 2026
Freedom Diagnostics · HPLC

For

NAD+

by Forge Performance Co.· batch Blue Cap

Aggregated · 3rd-party listing
99.35 %
Apr 2026
ILS Labs

For

NAD+

by Riptide Wellness· batch RWND-500-1003

Aggregated · 3rd-party listing
99.00 %
Apr 2026
ILS Labs · HPLC

For

NAD 500mg

by Crush Research· batch CRNAD-500-2604-2

Aggregated · 3rd-party listing
99.89 %
Apr 2026
Freedom Diagnostics · HPLC

For

NAD+

by Blank Peptides· batch 665394

Aggregated · 3rd-party listing
99.80 %
Mar 2026
Bioviridian · HPLC

For

NAD+

by Prime Peptides· batch 2172026ND

Aggregated · 3rd-party listing
99.70 %
Mar 2026
Freedom Diagnostics · HPLC

For

NAD+

by Peptide Supply Co.· batch NAD1K030526

Aggregated · 3rd-party listing
99.63 %
Mar 2026
Freedom Diagnostics · HPLC

For

NAD+

by Peptide Supply Co.· batch NAD5030526

Aggregated · 3rd-party listing
99.69 %
Mar 2026
Freedom Diagnostics

For

NAD+

by Real Peptides

Aggregated · 3rd-party listing
99.56 %
Mar 2026
Freedom Diagnostics

For

NAD+

by Real Peptides

Aggregated · 3rd-party listing
99.97 %
Feb 2026
Freedom Diagnostics · HPLC

For

NAD+

by Peptide Plugs· batch cmp96ij2m000a1wrxpsak0z7e

Aggregated · 3rd-party listing
99.80 %
Feb 2026
Vanguard Laboratory · HPLC

For

NAD+

by Mile High Compounds· batch NAD-500-MH-04

Aggregated · 3rd-party listing
99.90 %
Feb 2026
Analytical Formulations, Inc.

For

NAD+

by Ion Peptide

Aggregated · 3rd-party listing
99.40 %
Feb 2026
Analytical Formulations, Inc.

For

NAD+

by Ion Peptide

Aggregated · 3rd-party listing
99.63 %
Jan 2026
BioRegen · HPLC

For

NAD+

by BioLongevity Labs· batch 21-3-46035

Aggregated · 3rd-party listing
99.85 %
Jan 2026
Chromate · HPLC

For

NAD+

by Peptide Partners· batch NDU202601

Aggregated · 3rd-party listing
99.93 %
Jan 2026
Freedom Diagnostics · HPLC

For

NAD+

by Simple Peptide· batch NAD0116N26-H

Research depth

32 citations indexed for NAD+

All research on NAD+ →

review · 2026

Targeting NAD Homeostasis: Compartmentalization, Quantification, and Modulation

Nicotinamide adenine dinucleotide (NAD + ) and its reduced form, NADH, are essential coenzymes that play central roles in cellular redox homeostasis, energy metabolism, DNA repair, and signaling.

Study · 2026

Mitochondrial NAD<sup>+</sup> Transport Alleviates Cerebral Ischemia/Reperfusion Injury via Enhancement of Mitochondrial Function

Aims Cerebral ischemia-reperfusion (I/R) injury is a leading cause of neurological disability and is characterized by mitochondrial dysfunction and oxidative stress.

Study · 2026

Bacterial defense via RES-mediated NAD<sup>+</sup> depletion is countered by phage phosphatases

Many bacterial defense systems restrict phage infection by breaking down the molecule nicotinamide (Nam) adenine dinucleotide (NAD + ) into adenosine diphosphate ribose (ADPR) and Nam.

Study · 2026

Laser-Engineered Ag Nanoparticle on Carbon Cloth Electrodes for Enzyme-Free Electrochemical NAD<sup>+</sup> Detection

Nicotinamide adenine dinucleotide ( NAD+${\rm NAD}^+$ ) is a core redox cofactor, and its concentration reflects age and metabolic state, which has driven the development of NAD+${\rm NAD}^+$ biochemical analytical techniques.

animal · 2026

Glucocorticoid excess disrupts NAD+ homeostasis in male and female mice

Glucocorticoid excess induces a plethora of metabolic disturbances, including obesity, muscle atrophy, hepatic steatosis and increased energy expenditure, which are hallmark features of Cushing's syndrome.

review · 2026

NAD<sup>+</sup>‒circadian rhythm coupling in dementia

The circadian rhythm system and sleep coordinate whole-body functions across the 24-h cycle, yet these rhythms progressively deteriorate with neurodegenerative diseases, including dementia.