Melanotan II
Also known as: MT-2
Melanotan II (MT-II) is a cyclic heptapeptide analog of alpha-melanocyte-stimulating hormone (α-MSH) — Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2 — developed at the University of Arizona in the 1980s by Hruby, Hadley, and colleagues as a candidate photoprotection / sunless-tanning agent. It has never been approved by the FDA or any other regulator for any indication; clinical development was abandoned and it is sold only via grey-market research-chemical channels. Genuine safety signals have been reported, including darkening of existing moles, eruptive atypical nevi, and case reports of new primary melanoma in young tanning-seeking users.
Who's worth your money for Melanotan II
Every current seller, ranked by independent evidence — Merit Score, latest COA purity, and live $/mg (size-normalized). Prices refresh daily. Rankings are never paid.
Top Merit pick
Highest Merit Score (96) of 16 scored sellers
$28.00 · 10mg · 99.1% purity
Best value
Lowest $/mg among scored sellers
$240 · 100mg · 99.6% purity
Most tested
2 independent COAs on file
$40.00 · 10mg · 100.0% purity
Average price
$3.77/mg
Sellers
75
45-day trend
+1.2%
68 of 75 sellers have a current price· 36 stale hidden· 16 unverified hidden
Top Merit pick
🇺🇸 Moglabs96via Disclosed Labs · 23h ago
$2.80/mg -25.8% vs avg$28.00
10mg
- 🇺🇸 Prime Peptides95
✓ verified at source · 23h ago
$4.00/mg +6% vs avg$40.00
10mg
- 🇺🇸 Profound Aminos95
via Disclosed Labs · 23h ago
$6.50/mg +72.3% vs avg$65.00
10mg
- 🇺🇸 Licensed Peptides95
✓ verified at source · 23h ago
$6.60/mg +74.9% vs avg$65.99
10mg
no purityBuy code MERIT · 5% off - 🇺🇸 Peptide Tech94
✓ verified at source · 23h ago
$3.50/mg -7.2% vs avg$34.99
10mg
no purity - 🇺🇸 Forge Performance Co.94
✓ verified at source · 23h ago
$3.50/mg -7.2% vs avg$35.00
10mg
- 🇺🇸 Peptide Plugs89
✓ verified at source · 23h ago
$4.00/mg +6% vs avg$40.00
10mg
- 🇺🇸 Arcane Peptides88
via Disclosed Labs · 23h ago
$3.50/mg -7.2% vs avg$35.00
10mg
- 🇺🇸 EZ Peptides85
✓ verified at source · 23h ago
$4.40/mg +16.6% vs avg$44.00
10mg
- Peptide Supply Co.83
via Disclosed Labs · 23h ago
$2.40/mg -36.4% vs avg$240
100mg
Prices observed from public storefronts (last 24h), normalized to $/mg. "Evidence" is Merit's 0–100 Merit Score, derived only from observable verification evidence (methodology on /about); "Purity" is the latest independent COA. Some buy links are affiliate links — Merit may earn a commission at no extra cost to you, and where a vendor offers one, the code shown gets you a discount at their checkout. Affiliate status never affects price data, ranking, or the Merit Score (full policy on /disclosure). Research use only.
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About Melanotan II
CAS
121062-08-6
Molecular formula
C50H69N15O9
Sequence
Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2
Typical dose range
0.25–0.5 mg/day subcutaneous (loading); Phase I clinical starting dose 0.01 mg/kg/day SC
Half-life
~30–60 minutes
COAs for Melanotan II
60 third-party tests across 25 vendors. Each card links to the full report.
For
Melanotan-2 acetate
by Voltera Sciences· batch ML20.05.28.26
For
Melanotan II
by Crush Research· batch CR-MT2-10-2605-1
For
Melanotan II
by Verified Peptides· batch MT206260510E
For
MLT II
by Ion Peptide· batch MTII20-05072026
For
MLT II
by Ion Peptide· batch MTII20-05072026
For
Melanotan-2
by Real Peptides· batch Yellow Cap
For
Melanotan II
by Skye Peptides· batch MT226-10-001
For
Melanotan II
by Prime Peptides· batch 3092026MT2
For
Melanotan II
by Prime Peptides· batch 3132026MT2
For
MT2
by Riptide Wellness· batch RWMT2-10-1003
For
Melanotan II
by Moglabs· batch MT202
For
Melanotan II
by Arcane Peptides· batch MT202
For
Melanotan II
by Arcane Peptides· batch MT202
For
Melanotan II
by Moglabs· batch MT202
For
Melanotan II
by Peptide Plugs· batch 120-A-S
For
Melanotan-2
by OROS Research· batch OR-LPMT2-426-B5
For
Melanotan-2
by Glacier Aminos· batch MT210GA-03
For
Melanotan II
by Blank Peptides· batch 665394
For
Melanotan-2
by Crush Research· batch CR-MT210-2603-1
For
Melanotan-2
by Crush Research· batch CR-MT210-2603-1
For
Melanotan II
by Forge Performance Co.· batch Black Cap
For
Melanotan II
by Kimera Chems· batch KC-MT2-YEL2
For
Melanotan 2
by Peptide Supply Co.· batch MT21003232026
For
Melanotan-2
by Mile High Compounds· batch MLN-010-MH-01
13 citations indexed for Melanotan II
case-report · 2026
Changes in Oral Mucosa Associated with Melanotan II Injections: A Case Report
This case report presents a three-month follow-up of a patient who self-administered Melanotan II injections over a period of 64 days with the goal of achieving a deeper tanning effect. Melanotan II is an unlicensed synthetic peptide analog belonging to the melanocortin hormone family.
rct · 2026
Melanotan II (MT-II) as an Adjunct to NB-UVB Phototherapy for Repigmentation in Stable Nonsegmental Vitiligo
This example interventional study record describes a randomized Phase 2 clinical trial evaluating investigational Melanotan II (MT-II) as an adjunct to standard NB-UVB phototherapy for repigmentation in adults with stable nonsegmental vitiligo.
case-report · 2025
Melanotan II nasal spray: a possible risk factor for oral mucosal malignant melanoma?
The case of a 22-year-old female who developed a mass in the anterior maxilla after using Melanotan II, a nasal spray containing a synthetic analogue of melanocyte-stimulating hormone, is reported. The patient had used the nasal spray for tanning purposes.
animal · 2024
Antidepressant-like and antistress effects of the ACTH(4-10) synthetic analogs Semax and Melanotan II on male rats in a model of chronic unpredictable stress
Current antidepressant therapy shows substantial limitations, and there is an urgent need for the development of new treatment strategies for depression. Stressful events and hyperactivity of the hypothalamic-pituitary-adrenal (HPA) axis play an important role in the pathogenesis of depression.
Study · 2024
5-Hydroxypyrroloindoline Affords Tryptathionine and 2,2'-bis-Indole Peptide Staples: Application to Melanotan-II
With peptides increasingly favored as drugs, natural product motifs, namely the tryptathionine staple, found in amatoxins and phallotoxins, and the 2,2'-bis-indole found in staurosporine represent unexplored staples for unnatural peptide macrocycles.
animal · 2023
Melanotan-II reverses memory impairment induced by a short-term HF diet
A high-fat (HF) diet has been shown to increase the risk of neurological impairments and neurodegenerative disorders. The melanotropins used in this study have been associated with diet-related disorders; however, there is an absence of studies on their effect on diet-induced neurobehavioral conditions.