Melanotan I
Also known as: Afamelanotide
Melanotan I (Afamelanotide) is a synthetic analog of alpha-MSH that selectively activates MC1R. FDA-approved as Scenesse for erythropoietic protoporphyria (EPP), it is distinct from Melanotan II and is studied for melanogenesis and photoprotection.
Who's worth your money for Melanotan I
Every current seller, ranked by independent evidence — Merit Score, latest COA purity, and live $/mg (size-normalized). Prices refresh daily. Rankings are never paid.
Top Merit pick
Highest Merit Score (96) of 24 scored sellers
$28.00 · 10mg · 99.6% purity
Best value
Lowest $/mg among scored sellers
$48.00 · 100mg
Most tested
6 independent COAs on file
$55.97 · 10mg · 99.8% purity
Average price
$4.16/mg
Sellers
45
45-day trend
+2.1%
36 of 45 sellers have a current price· 7 stale hidden· 5 unverified hidden
Top Merit pick
🇺🇸 Moglabs96✓ verified at source · 9h ago
$2.80/mg -32.8% vs avg$28.00
10mg
- 🇺🇸 BioLongevity Labs96
via Disclosed Labs · 10h ago
$5.60/mg +34.4% vs avg$55.97
10mg
- 🇺🇸 Prime Peptides95
via Disclosed Labs · 10h ago
$4.50/mg +8.1% vs avg$45.00
10mg
- 🇺🇸 Profound Aminos95
via Disclosed Labs · 10h ago
$5.50/mg +32.1% vs avg$55.00
10mg
- 🇺🇸 Licensed Peptides95
✓ verified at source · 3d ago · stale
$8.80/mg +111.3% vs avg$87.99
10mg
no purityBuy Code MERIT · 5% off - 🇺🇸 Polaris Peptides90
via Disclosed Labs · 10h ago
$3.85/mg -7.6% vs avg$50.00
13mg
no purity - 🇺🇸 Peptide Plugs89
✓ verified at source · 1d ago
$4.00/mg -4% vs avg$40.00
10mg
no purity - 🇺🇸 Soma Peptides89
✓ verified at source · 1d ago
$4.90/mg +17.7% vs avg$49.00
10mg
no purity - 🇺🇸 Arcane Peptides88
via Disclosed Labs · 10h ago
$3.50/mg -16% vs avg$35.00
10mg
- 🇺🇸 Ruo Bio88
✓ verified at source · 9h ago
$3.80/mg -8.8% vs avg$38.00
10mg
Prices observed from public storefronts (last 24h), normalized to $/mg. "Evidence" is Merit's 0–100 Merit Score, derived only from observable verification evidence (methodology on /about); "Purity" is the latest independent COA. Some buy links are affiliate links — Merit may earn a commission at no extra cost to you, and where a vendor offers one, the code shown gets you a discount at their checkout. Affiliate status never affects price data, ranking, or the Merit Score (full policy on /disclosure). Research use only.
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About Melanotan I
CAS
75921-69-6
Molecular formula
C78H111N21O19
Sequence
SYSNEHFRWGKPV
Typical dose range
16 mg subcutaneous implant every 2 months (approved EPP regimen); research injection doses of 0.08–0.21 mg/kg/day subcutaneous used in early trials
Half-life
~30–50 minutes (plasma elimination half-life after subcutaneous injection; implant formulation releases over ~10 days)
COAs for Melanotan I
54 third-party tests across 23 vendors. Each card links to the full report.
For
Melanotan I
by Ion Peptide· batch MLTI10-06102026
For
Melanotan I
by Ion Peptide· batch MLT110-06102026
For
MLT I
by Ion Peptide· batch MTI10-05072026
For
MLT I
by Ion Peptide· batch MTI10-05072026
For
Melanotan I
by Moglabs· batch MT102
For
Melanotan I
by Arcane Peptides· batch MT102
For
MT1
by Riptide Wellness· batch RWMT1-10-1002
For
Melanotan I
by Arcane Peptides· batch MT102
For
Melanotan I
by Moglabs· batch MT102
For
Melanotan I
by Amino Club· batch MI0001
For
Melanotan-1
by Crush Research· batch CR-MT110-2603-1
For
Melanotan-1
by Crush Research· batch CR-MT110-2603-1
For
Melanotan I
by Simple Peptide· batch MT104232026-4
For
Melanotan 1
by Peptide Supply Co.· batch MT11003232026
For
Melanotan-1
by Orbitrex Peptides· batch MT1100426
For
Melanotan-1
by Mile High Compounds· batch MT1-010-MH-01
For
Melanotan-I
by Puratek Peptides· batch Mt10001
For
Melanotan-1
by Skye Peptides· batch MT126-10-001
For
Melanotan-1
by Ion Peptide· batch MLT110-011226
For
Melanotan I
by Kimera Chems· batch KC-MT1-YEL1
For
Melanotan I
by Glacier Aminos· batch MT10GA01
For
Melanotan 1
by Hydro Research Peptides· batch HYDROCP7QHN3
For
Melanotan I
by Ruo Bio· batch RUOV2912T92H
For
Melanotan I
by Peptide Supply Co.· batch cmpa6pnxe000t73rxrsgy091k
12 citations indexed for Melanotan I
case-report · 2026
Five primary melanomas in situ in a patient with recent tanning bed use, melanotan exposure, and anabolic hormone use
review · 2026
Insights into Tanning Biology and Tanning Products
Objective This systematic review aims to critically assess the literature on the mechanisms of action, clinical uses, formulation strategies, and adverse effects of self-tanning agents, with a focus on dihydroxyacetone (DHA), melanotan, forskolin, and carotenoids.
review · 2026
Molecular Targets in Modern Cosmetic Science
review · 2026
Rationale of renewed efforts in developing MC4R modulators to treat metabolic disorders
The melanocortin-4 receptor (MC4R) is a key regulator of energy balance and a potential target for weight management. Early drug discovery endeavors were hindered by incomplete understanding of its signal transduction mechanisms and broad activation of G s pathways.
case-report · 2026
Changes in Oral Mucosa Associated with Melanotan II Injections: A Case Report
This case report presents a three-month follow-up of a patient who self-administered Melanotan II injections over a period of 64 days with the goal of achieving a deeper tanning effect. Melanotan II is an unlicensed synthetic peptide analog belonging to the melanocortin hormone family.
Study · 2025
A single-centre, prospective, qualitative analysis of knowledge, attitudes and behaviour of sunbed use among patients attending a pigmented lesion clinic in a tertiary referral centre
Background Indoor tanning through sunbeds is linked to a heightened risk of skin cancers, particularly cutaneous squamous cell carcinoma and basal cell carcinoma, with significant increases in risk for users aged Objectives To analyse the characteristics, attitudes and behaviours of sunbed users attending an Irish derm…