LL-37
Also known as: Cathelicidin
LL-37 is the only human cathelicidin antimicrobial peptide — a 37-amino-acid peptide (starting with two leucines) cleaved from the hCAP-18 precursor. It has broad-spectrum antimicrobial activity and immunomodulatory roles, but is also implicated in the pathogenesis of autoimmune and inflammatory skin diseases including psoriasis, rosacea, and lupus. Not FDA-approved; research-use only.
Who's worth your money for LL-37
Every current seller, ranked by independent evidence — Merit Score, latest COA purity, and live $/mg (size-normalized). Prices refresh daily. Rankings are never paid.
Top Merit pick
Highest Merit Score (96) of 11 scored sellers
$94.97 · 5mg · 99.8% purity
Best value
Lowest $/mg among scored sellers
$49.99 · 10mg
Most tested
6 independent COAs on file
$45.00 · 5mg · 99.6% purity
Average price
$12.24/mg
Sellers
44
45-day trend
+7.3%
35 of 44 sellers have a current price· 6 stale hidden· 18 unverified hidden
Top Merit pick
🇺🇸 BioLongevity Labs96✓ verified at source · 23h ago
$18.99/mg +55.1% vs avg$94.97
5mg
- 🇺🇸 Orbitrex Peptides95
via Disclosed Labs · 23h ago
$9.00/mg -26.5% vs avg$44.99
5mg
- 🇺🇸 Ion Peptide95
✓ verified at source · 23h ago
$9.00/mg -26.5% vs avg$45.00
5mg
- 🇺🇸 Peptide Tech94
✓ verified at source · 23h ago
$5.00/mg -59.2% vs avg$49.99
10mg
no purity - 🇺🇸 Peptide Plugs89
✓ verified at source · 23h ago
$12.00/mg -2% vs avg$60.00
5mg
no purity - 🇺🇸 Verified Peptides86
via Disclosed Labs · 23h ago
$13.14/mg +7.3% vs avg$65.70
5mg
- 🇺🇸 EZ Peptides85
✓ verified at source · 23h ago
$7.80/mg -36.3% vs avg$78.00
10mg
- 🇺🇸 Ascension Peptides83
via Disclosed Labs · 23h ago
$8.90/mg -27.3% vs avg$89.00
10mg
- 🇺🇸 MedGe Peptides82
✓ verified at source · 23h ago
$25.00/mg +104.2% vs avg$125
5mg
- 🇺🇸 Texpeptide69
✓ verified at source · 23h ago
$8.00/mg -34.7% vs avg$40.00
5mg
no purity
Prices observed from public storefronts (last 24h), normalized to $/mg. "Evidence" is Merit's 0–100 Merit Score, derived only from observable verification evidence (methodology on /about); "Purity" is the latest independent COA. Some buy links are affiliate links — Merit may earn a commission at no extra cost to you, and where a vendor offers one, the code shown gets you a discount at their checkout. Affiliate status never affects price data, ranking, or the Merit Score (full policy on /disclosure). Research use only.
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About LL-37
CAS
154947-66-7
Molecular formula
C205H340N60O53
Sequence
LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES
Typical dose range
100–400 mcg/day subcutaneous
Half-life
~4–6 hours (tissue-dependent; limited formal PK data for native LL-37)
COAs for LL-37
42 third-party tests across 12 vendors. Each card links to the full report.
For
LL-37
by Ion Peptide· batch L375-06092026
For
LL-37
by Ion Peptide· batch L375-06092026
For
LL-37
by Verified Peptides· batch LL05260305C
For
LL-37
by Verified Peptides
For
LL-37
by Verified Peptides· batch LL025602005C
For
LL-37
by Real Peptides· batch Black Cap
For
LL-37
by Ion Peptide· batch LL375-03232026
For
LL-37
by Ion Peptide· batch LL375-03232026
For
LL-37
by EZ Peptides· batch EZP-LL371002172026-01
For
LL-37
by EZ Peptides· batch EZP-LL37100217-2026-01
For
LL-37
by Peptidology· batch 1669
For
LL-37
by Ruo Bio
For
LL-37
by Simple Peptide· batch L1-05-01162026-J
For
LL-37
by Simple Peptide· batch LL10-37011220236-J
For
LL-37
by MedGe Peptides· batch LL375LT12
For
LL-37
by MedGe Peptides· batch LL375LT12
For
LL-37
by Simple Peptide· batch LL37L2092025-J
For
LL-37
by Orbitrex Peptides· batch LL5126
For
LL-37
by Orbitrex Peptides
For
LL-37
by Real Peptides
For
LL-37
by Kimera Chems· batch KC-L37-BLU1
For
LL-37
by Mile High Compounds· batch LL3-005-MH-01
For
LL-37
by Mile High Compounds· batch LL3-005-MH-01
For
LL-37
by BioLongevity Labs· batch 251549
20 citations indexed for LL-37
review · 2026
LL-37: Biological Mechanisms and Emerging Therapeutic Applications in Intestinal Disease
Human cathelicidin peptide LL-37 is encoded by the CAMP gene and plays a key role in innate immunity. It maintains intestinal homeostasis through antibacterial, immunomodulation, and tissue repair functions.
Study · 2026
LL-37 and citrullinated-LL-37 enhances oxylipins: citrullination attenuates LL-37-mediated COX-2-dependent chemokine response in human bronchial epithelial cells
BACKGROUND: During airway inflammation, chemokines, oxylipins (bioactive lipids) and cationic host defence peptides (CHDP) are enhanced in the lungs. However, the interplay of these molecules in the process of airway inflammation is not fully resolved.
review · 2026
β-Amyloid (Aβ) and Human Cathelicidin LL-37: Two Sides of the Same Coin?
Study · 2026
A degradable hydrogel scaffold incorporating the LL-37 for gingival soft tissue regeneration
Gingival recession exposes the roots, leads to dentin hypersensitivity, and heightens the progression of periodontitis, and poses a threat to oral health and appearance. Conventional treatment uses autogenous palatal grafts, requiring a second surgical site and adding patient discomfort.
review · 2026
β-Amyloid (Aβ) and Human Cathelicidin LL-37: Two Sides of the Same Coin?
Physiologically produced circulating β-amyloid (Aβ) exerts critical physiological functions. Although Aβ is a key player in Alzheimer's disease (AD), it may initially be beneficial at the onset of infection.
Study · 2026
[Evaluation of Serum LL-37 Levels in Patients with Brucellosis and Their Relationship with Clinical Course]
This study aimed to determine the serum levels of the LL-37 molecule, associated with the pathophysiology of Brucellosis, in patients diagnosed with Brucellosis and to investigate the relationship between these levels and the clinical course of the disease.