KPV
Also known as: Lysine-Proline-Valine (alpha-MSH 11-13)
KPV is the C-terminal tripeptide of alpha-melanocyte-stimulating hormone (alpha-MSH), corresponding to residues 11-13. It is the smallest alpha-MSH fragment shown to retain anti-inflammatory activity. Research-only; not FDA-approved; evidence is primarily preclinical.
Who's worth your money for KPV
Every current seller, ranked by independent evidence — Merit Score, latest COA purity, and live $/mg (size-normalized). Prices refresh daily. Rankings are never paid.
Top Merit pick
Highest Merit Score (99) of 38 scored sellers
$51.99 · 10mg · 99.2% purity
Best value
Lowest $/mg among scored sellers
$161 · 100mg · 99.4% purity
Most tested
15 independent COAs on file
$55.00 · 10mg · 99.6% purity
Average price
$5.97/mg
Sellers
68
45-day trend
-2.2%
55 of 68 sellers have a current price· 5 stale hidden· 12 unverified hidden
Top Merit pick
🇺🇸 Glacier Aminos99✓ verified at source · 10h ago
$5.20/mg -12.8% vs avg$51.99
10mg
- 🇺🇸 Peptide Partners99
✓ verified at source · 9h ago
$8.80/mg +47.5% vs avg$88.00
10mg
- 🇺🇸 Hydro Research Peptides97
✓ verified at source · 9h ago
$5.50/mg -7.8% vs avg$55.00
10mg
- 🇺🇸 Moglabs96
✓ verified at source · 9h ago
$6.00/mg +0.6% vs avg$30.00
5mg
- 🇺🇸 BioLongevity Labs96
✓ verified at source · 9h ago
$10.00/mg +67.6% vs avg$99.97
10mg
- 🇺🇸 Profound Aminos95
via Disclosed Labs · 10h ago
$5.00/mg -16.2% vs avg$50.00
10mg
- 🇺🇸 Licensed Peptides95
✓ verified at source · 9h ago
$7.70/mg +29.1% vs avg$76.99
10mg
- 🇺🇸 Sunrise Bioresearch94
via Disclosed Labs · 10h ago
$1.61/mg -73% vs avg$161
100mg
- 🇺🇸 Peptide Crafters94
✓ verified at source · 10h ago
$4.00/mg -32.9% vs avg$40.00
10mg
- 🇺🇸 Forge Performance Co.94
✓ verified at source · 9h ago
$4.05/mg -32.1% vs avg$40.50
10mg
no purityBuy Code MERIT · 10% off
Prices observed from public storefronts (last 24h), normalized to $/mg. "Evidence" is Merit's 0–100 Merit Score, derived only from observable verification evidence (methodology on /about); "Purity" is the latest independent COA. Some buy links are affiliate links — Merit may earn a commission at no extra cost to you, and where a vendor offers one, the code shown gets you a discount at their checkout. Affiliate status never affects price data, ranking, or the Merit Score (full policy on /disclosure). Research use only.
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About KPV
CAS
67727-97-3
Molecular formula
C16H30N4O4
Sequence
KPV
Typical dose range
250–500 mcg/day subcutaneous (research use)
Half-life
~4–6 hours (rodent pharmacokinetic data; human data lacking)
COAs for KPV
161 third-party tests across 40 vendors. Each card links to the full report.
For
KPV
by Rescue Research USA· batch RR-KPV-2609
For
KPV
by Sunrise Bioresearch· batch KPVJUN26-01
For
KPV
by Sunrise Bioresearch· batch KPVJUN26-01
For
KPV
by jdbioworks· batch 2026-002
For
KPV
by NG Peptide· batch KP10-06
For
KPV
by Peptide Plugs· batch 101-05-ZB
For
KPV
by Ignite Peptides· batch KPV1012321
For
KPV
by OROS Research· batch OR-LPKPV15-626-B3
For
KPV
by Optima Supply· batch OS-2026-1179
For
KPV
by Hydro Research Peptides· batch HR-2026-4981
For
KPV
by optimasupply.is· batch OS-2026-1179
For
KPV
by Apexx Biolabs· batch Purple Cap-1
For
KPV
by Mile High Compounds· batch KPV-010-MH-05
For
KPV
by Soma Peptides· batch KPX062609
For
KPV
by Peptide Partners· batch SPL-4157
For
KPV
by Peptide Partners· batch KV202606
For
KPV
by Peptide Supply Co.· batch KPV10 06032026
For
KPV
by Crush Research· batch CR-KPV-10-2605-1
For
KPV
by Moglabs· batch KPV002
For
KPV
by EZ Peptides· batch EZP-KPV1005152026-12
For
KPV
by EZ Peptides· batch EZP-KPV1005152026-12
For
KPV
by True Peptide· batch KPV1-019-TPL
For
KPV
by Modern Research Peptides· batch BCRTHK23461
For
KPV
by Nox Amino· batch NA-KP0526-01
12 citations indexed for KPV
animal · 2026
KPV attenuates adipogenesis and lipid metabolism through modulation of ROS-mediated AKT/mTORC1/PPARγ signaling
Lysine-Proline-Valine (KPV), an endogenous tripeptide derived from α-melanocyte-stimulating hormone, has been recognized for its anti-inflammatory and antioxidant activities. However, its role in adipocyte differentiation has not been investigated.
Study · 2026
Lysine-proline-valine peptide attenuates hepatic lipid accumulation through ROS-dependent regulation of the PPARγ pathway in HepG2 cells
Hepatocellular steatosis, an early stage within the non-alcoholic fatty liver disease (NAFLD) spectrum, is characterized by excessive lipid accumulation and oxidative stress in hepatocytes.
in-vitro · 2026
Exploration of 1,3,4-Thiadiazole Bearing Quinolin-2(1H)-One Hybrids as Potent Antimycobacterial Agents: Design, Synthesis, and In Silico Docking Techniques
Introduction The development of novel quinolin-2(1H)-one-fused 1,3,4-thiadiazole heterocyclic hybrids was achieved through structural optimization as potential antimicrobial/anti- TB agents.
Study · 2026
Inflammation-triggered self-immolative conjugates enable oral peptide delivery by overcoming gastrointestinal barriers
Oral delivery of peptide therapeutics remains challenging due to gastrointestinal (GI) degradation and poor intestinal absorption.
Study · 2026
Bioinspired microcapsule reactor with engineered probiotics for IBD therapy
Although probiotic-based bionic strategies show therapeutic promise for inflammatory bowel disease, their clinical translation is limited by poor gastric acid survival, inefficient intestinal colonization and inadequate targeting.
Study · 2026
Pediatric Neuroinflammatory and Neuropsychiatric Syndromes Associated with Dupilumab Treatment for Atopic Dermatitis
Dupilumab, a monoclonal antibody blocking interleukin-4/interleukin-13 signaling, was associated with neuroinflammatory syndromes in 4 children treated for atopic dermatitis. Individuals exhibited behavioral changes, language impairment, and neurodiagnostic abnormalities 2-6 months after treatment initiation.