Humanin
Also known as: HN
Humanin is a mitochondrial-derived peptide encoded within the 16S ribosomal RNA gene. It was discovered through its ability to protect neurons from Alzheimer's disease-related toxicity and is studied for neuroprotection, metabolic regulation, and anti-aging applications.
Who's worth your money for Humanin
Every current seller, ranked by independent evidence — Merit Score, latest COA purity, and live $/mg (size-normalized). Prices refresh daily. Rankings are never paid.
Top Merit pick
Highest Merit Score (99) of 1 scored sellers
$165 · 10mg · 99.9% purity
Average price
$12.88/mg
Sellers
12
45-day trend
+10.9%
7 of 12 sellers have a current price· 1 stale hidden· 5 unverified hidden
- 🇺🇸 Peptide Partners99
✓ verified at source · 3d ago
$16.50/mg +28.1% vs avg$165
10mg
Prices observed from public storefronts (last 24h), normalized to $/mg. "Evidence" is Merit's 0–100 Merit Score, derived only from observable verification evidence (methodology on /about); "Purity" is the latest independent COA. Some buy links are affiliate links — Merit may earn a commission at no extra cost to you, and where a vendor offers one, the code shown gets you a discount at their checkout. Affiliate status never affects price data, ranking, or the Merit Score (full policy on /disclosure). Research use only.
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About Humanin
CAS
330936-69-1
Molecular formula
C119H204N34O32S2
Sequence
MAPRGFSCLLLLTSEILDLPVKRRA
Typical dose range
0.5–2 mg subcutaneous injection, daily to 3x weekly (research use only; no established clinical dose)
Half-life
~0.5–4 hours (native humanin: ~5–15 min plasma half-life; HNG analogue has extended activity)
COAs for Humanin
6 third-party tests across 2 vendors. Each card links to the full report.
For
Humanin
by Kimera Chems· batch KC-HMN-PUR1
For
Humanin
by Ruo Bio
For
Humanin
by Peptide Partners· batch HP20250805
For
Humanin
by Peptide Partners· batch HP20250805
Purity not on file
For
Humanin
by Peptide Partners· batch HP20250805
Purity not on file
For
Humanin
by Ruo Bio
19 citations indexed for Humanin
Study · 2026
Humanin Attenuates Inflammatory Liver Injury and NF-κB Activation During Systemic Hypervirulent <i>Klebsiella pneumoniae</i> Infection
Hypervirulent Klebsiella pneumoniae (hvKP) causes invasive infections, including bloodstream infections and liver abscesses, and dysregulated host inflammation may exacerbate liver injury.
review · 2026
Mitochondrial-derived peptides in female reproduction: Emerging regulators of oocyte competence and novel therapeutic opportunities for infertility
Female infertility affects approximately 17.5% of adults worldwide.
review · 2026
The MTRNR2L gene family and age-related macular degeneration
Age-related macular degeneration (AMD) is the leading cause of blindness in aging adults, yet no FDA-approved therapies exist for early and intermediate disease.
Study · 2026
[Effects of cardiac rehabilitation and predictive value of Humanin/CRP ratio in patients with acute exacerbation of chronic heart failure]
Objective: To evaluate the effects of a standardized rehabilitation protocol on physical performance, exercise tolerance, and prognosis in hospitalized patients with acute exacerbation of chronic heart failure (CHF), and to explore the clinical value of the serum Humanin (a mitochondria-derived peptide) to C-reactive p…
Study · 2026
Humanin variants differentially regulate BID fibrilization and suppress BAX- and BID-dependent membrane permeabilization
Humanin (HN), a mitochondria-derived peptide, exerts cytoprotective effects by modulating apoptosis through interactions with pro-apoptotic BCL-2 proteins, BAX and BID.
animal · 2026
Humanin attenuates neuronal cellular senescence and preserves neurotransmitter release in differentiated PC12 cells
Cellular senescence, characterized as a permanent arrest of cell proliferation, is triggered by various types of stress. Senescent cells are identified by markers, including senescence-associated β-galactosidase (SA-β-gal) activity and the secretion of senescence-associated secretory phenotype (SASP) factors.