hCG
Also known as: Human Chorionic Gonadotropin, Chorionic Gonadotropin, Pregnyl, Novarel, Ovidrel
Human chorionic gonadotropin is a placental glycoprotein hormone composed of a 92-amino-acid alpha subunit (shared with LH, FSH, and TSH) and a distinct 145-amino-acid beta subunit, joined non-covalently and heavily glycosylated. It acts as an agonist at the luteinizing hormone/choriogonadotropin receptor (LHCGR), mimicking the LH surge. In females it sustains the corpus luteum and progesterone production in early pregnancy and triggers final oocyte maturation and ovulation; in males it stimulates testicular Leydig cells to produce intratesticular testosterone, supporting spermatogenesis. hCG is FDA-approved (e.g., Pregnyl, Novarel, recombinant Ovidrel) for ovulation induction, assisted reproduction, and male hypogonadism/cryptorchidism.
Who's worth your money for hCG
Every current seller, ranked by independent evidence — Merit Score, latest COA purity, and live $/mg (size-normalized). Prices refresh daily. Rankings are never paid.
Average price
—/mg
Sellers
22
45-day trend
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0 of 22 sellers have a current price
Prices observed from public storefronts (last 24h), normalized to $/mg. "Evidence" is Merit's 0–100 Merit Score, derived only from observable verification evidence (methodology on /about); "Purity" is the latest independent COA. Some buy links are affiliate links — Merit may earn a commission at no extra cost to you, and where a vendor offers one, the code shown gets you a discount at their checkout. Affiliate status never affects price data, ranking, or the Merit Score (full policy on /disclosure). Research use only.
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About hCG
CAS
9002-61-3
Molecular formula
—
Typical dose range
Fertility (final oocyte maturation): single 5,000-10,000 IU intramuscular or subcutaneous. Male TRT adjunct: commonly 250-500 IU subcutaneous 2-3x weekly (protocols vary, up to ~1,500 IU)
Half-life
~24-36 hours terminal half-life after IM/SC injection (biphasic; longer than LH due to glycosylation)
Common research uses
Safety notes
FDA-approved prescription drug; prescription-only in the US. Risks include ovarian hyperstimulation syndrome (OHSS) in women, thromboembolism, gynecomastia and fluid retention in men, and injection-site reactions. hCG is prohibited in men at all times under the WADA Code (S2 peptide hormones); homeopathic/weight-loss hCG products are not FDA-approved and are considered illegal/fraudulent.
Reconstitution
Lyophilized urinary hCG is reconstituted with the supplied bacteriostatic diluent; refrigerate after reconstitution and use within the labeled window. Recombinant hCG (Ovidrel) is supplied prefilled.
COAs for hCG
25 third-party tests across 9 vendors. Each card links to the full report.
For
HCG
by Genetic Peptide· batch F20350627
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For
HCG
by Certified Peptides· batch 260417HC50003
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For
HCG
by Peptidegurus· batch 24th Feb 2026
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For
hCG
by Moglabs· batch HCG002
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For
hCG
by Arcane Peptides· batch HCG002
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For
hCG 5000 IU
by Arcane Peptides· batch HCG002
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For
hCG 5000 IU
by Moglabs· batch HCG002
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For
HCG
by Bulk Peptides· batch HCG002
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For
HCG
by Moglabs· batch HCG002
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For
HCG
by Arcane Peptides· batch HCG002
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For
HCG
by Kimera Chems· batch KC-HCG-WHT1
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For
hCG 10000 IU
by Ruo Bio· batch RUOJZSC64Z76
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For
HCG
by Certified Peptides· batch HCG05425
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For
HCG 5000 iu
by Kimera Chems· batch Blue Cap
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For
HCG
by Certified Peptides· batch HCG05425
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For
HCG
by Kimera Chems· batch KC-HCG-RED2
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For
HCG
by Kimera Chems· batch Blue Cap
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For
HCG
by Forge Performance Co.· batch Orange Cap
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For
HCG
by Arcane Peptides
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For
HCG
by Ruo Bio
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For
HCG
by Moglabs
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For
HCG
by Nova Peptides· batch NV-P-XJ18
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For
HCG
by Nova Peptides· batch NV-P-XJ18
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For
HCG
by Nova Peptides· batch NV-P-IWQN
20 citations indexed for hCG
Study · 2026
Evaluation and performance of the β-hCG discriminatory zone and targeted ultrasound findings for early pregnancy diagnosis in a high-risk population: a retrospective cohort study at a US safety-net hospital
Study · 2026
Optimization of Pregnancy Testing in the Emergency Department: A Quality Improvement Initiative
Background At our institution, a review of emergency department pregnancy testing identified excess use of serum quantitative (quant) human chorionic gonadotropin (hCG) when only a binary result was clinically indicated. Additionally, we observed delays in point-of-care (POCT) urine hCG turnaround time.
case-report · 2026
Choriocarcinoma at an Abdominal Wall Cesarean Scar: Recurrence After Multi-Line Chemotherapy and Exploration of Salvage Therapy
Choriocarcinoma arising at an abdominal wall cesarean scar is not only exceedingly rare and diagnostically challenging but also represents a therapeutic dilemma, particularly when it becomes chemoresistant or relapses after multi-line chemotherapy.
Study · 2026
Pregnancy testing prior to iodine-131 thyroid therapy: a literature review of current recommendations
case-report · 2026
Pulmonary Epithelioid Trophoblastic Tumor Without Demonstrable Uterine Involvement: A Case Report and Literature Review Highlighting Diagnostic Challenges and Multidisciplinary Management
cohort · 2026
Buserelin Improves Ovulation-Embryo Synchrony Compared With hCG After eCG-Induced Superovulation in Donor Sows
This study directly compares hCG and buserelin as ovulation-inducing agents following eCG-based superovulation in weaned donor sows, focusing on their practical impact on ovulation-embryo synchrony under field conditions.