For research use only. Not for human consumption. Not medical advice — consult a licensed clinician.

Growth Hormone Secretagogues

Gonadorelin

Also known as: GnRH

Gonadorelin is a synthetic decapeptide identical to endogenous gonadotropin-releasing hormone (GnRH/LHRH; sequence pyroGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2). It was historically FDA-approved as Factrel (diagnostic GnRH stimulation test) and Lutrepulse (pulsatile IV pump for hypothalamic amenorrhea); both products are discontinued in the US. Gonadorelin remains on the FDA Category 1 bulk substances list and is widely compounded, most commonly as an off-label adjunct to TRT intended to preserve HPG-axis signaling.

Where to buy · live market data

Who's worth your money for Gonadorelin

Every current seller, ranked by independent evidence — Merit Score, latest COA purity, and live $/mg (size-normalized). Prices refresh daily. Rankings are never paid.

Top Merit pick

Highest Merit Score (94) of 2 scored sellers

$14.99/mg

$29.99 · 2mg

no COAs yet

Best value

Lowest $/mg among scored sellers

$10.50/mg

$105 · 10mg

no COAs yet

Average price

$11.60/mg

Sellers

16

45-day trend

+5.5%

12 of 16 sellers have a current price· 2 stale hidden· 8 unverified hidden

Prices observed from public storefronts (last 24h), normalized to $/mg. "Evidence" is Merit's 0–100 Merit Score, derived only from observable verification evidence (methodology on /about); "Purity" is the latest independent COA. Some buy links are affiliate links — Merit may earn a commission at no extra cost to you, and where a vendor offers one, the code shown gets you a discount at their checkout. Affiliate status never affects price data, ranking, or the Merit Score (full policy on /disclosure). Research use only.

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Compound reference

About Gonadorelin

CAS

33515-09-2

Molecular formula

C55H75N17O13

Sequence

QHWSYGLRPG

Typical dose range

100–250 mcg subcutaneous, 2–3x weekly (research use); 5–20 mcg/pulse every 90–120 min via pulsatile infusion pump for hypogonadotropic hypogonadism

Half-life

Distribution: 2–10 minutes; terminal: 10–40 minutes

Research depth

20 citations indexed for Gonadorelin

All research on Gonadorelin →

Study · 2026

Diagnostic Usefulness of Subcutaneous Triptorelin Stimulation Testing in the Evaluation of Central Precocious Puberty in Girls

The limited availability of gonadorelin has resulted in an increased use of subcutaneous triptorelin to diagnose central precocious puberty; however, studies validating its diagnostic value remain limited.

in-vitro · 2026

Recombinant bovine somatotropin at synchronization initiation, but not at embryo transfer, enhances fertility in embryo-recipient heifers: Associations with follicular, luteal, and embryonic outcomes

The aim of this study was to evaluate the effects of administering 325 mg of recombinant bovine somatotropin (rbST) at the initiation of the synchronization protocol (SYNCd) and/or on the day of embryo transfer (ETd) using a 2 × 2 experimental arrangement in Holstein heifer recipients.

animal · 2026

Increasing gonadorelin hydrochloride dose at the first GnRH of breeding Ovsynch enhances luteinizing hormone release, ovulatory response, and pregnancy in first-service lactating dairy cows

The objective of this study was to evaluate the effect of administering 200 µg versus 100 µg of GnRH as gonadorelin hydrochloride (Factrel; Zoetis, Parsippany, NJ) at the first GnRH injection (G1) of the breeding Ovsynch in a Double-Ovsynch (DO) protocol on pregnancy per artificial insemination (P/AI) at first service…

review · 2026

The neuroendocrine basis for parental care in teleost fish

Parental care enhances offspring survival but requires profound alteration of parental physiological and behavioural states.

animal · 2026

Estradiol treatment and double dose of GnRH for resynchronization protocols and timed artificial insemination in lactating dairy cows

The aim of this study was to compare pregnancy per AI (P/AI) in resynchronization (Resynch) protocols using different hormonal combinations (estradiol benzoate [EB], a double dose of GnRH, or EB with a double dose of GnRH) administered on the day of progesterone (P4) device insertion.

animal · 2026

Stress-related cortisol and progesterone concentrations influence the success of ovulation induction in estrous cats

Queens are induced ovulators, and ovulatory success varies with hormonal status and stress.