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Growth Hormone Secretagogues

GHRP-2

Also known as: Growth Hormone Releasing Peptide-2

GHRP-2 (pralmorelin) is a synthetic hexapeptide ghrelin receptor agonist that stimulates pituitary growth hormone release. It is approved in Japan (Kaken Pharmaceutical, 2004) as a single-dose diagnostic agent for GH deficiency, but is NOT FDA-approved in the US and is research-only. Unlike ipamorelin, GHRP-2 is non-selective and modestly raises ACTH, cortisol, and prolactin.

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Research depth

14 citations indexed for GHRP-2

All research on GHRP-2 →

Study · 2026

Growth Hormone-Releasing Peptides: Investigation of Their Secondary Structure, Thermal Stability, and Model Membrane Interactions

Growth hormone-releasing peptides (GHRPs) comprise a group of small synthetic peptides that can effectively influence growth hormone secretion both in humans and animals.

review · 2026

Pituitary dysfunction in trans-sellar encephalocele: a two-case report and a literature review

Trans-sellar encephalocele (TSE) is a rare congenital anomaly of the cranial base characterized by herniation of intracranial contents through the sellar floor. Although clinical presentations are diverse, the prevalence and characteristics of endocrine dysfunction due to hypothalamic-pituitary involvement are unclear.

Study · 2026

Behavioral Therapy Ameliorates Severe Obesity With Low Levels of Plasma GH and IGF-1: A Case Report

We encountered a patient with a body mass index of 50.7 kg/m 2 . Behavioral therapy was effective for preventing progression of health disturbance in this case. When coping with severe obesity, we must promote various tests to differentiate secondary obesity.

Study · 2026

Possible Involvement of Hypothalamic Dysfunction in Long COVID Patients Characterized by Delayed Response to Gonadotropin-Releasing Hormone

Long COVID (LC) may involve endocrine dysfunction; however, the underlying mechanism remains unclear.

review · 2026

Thyrotroph Pituitary Neuroendocrine Tumors: Molecular Pathology, Diagnostic Challenges, and Receptor-Targeted Therapeutic Strategies

review · 2026

Systematic review of undeclared prohibited substances and pharmacological adulterants in dietary supplements: prevalence, detection, and risks in sport

Introduction The proliferation of dietary supplement use among athletes has heightened concerns over inadvertent doping due to contamination with substances prohibited by the World Anti-Doping Agency (WADA) and other undeclared pharmacological adulterants.