GHK
Also known as: Glycyl-L-Histidyl-L-Lysine
GHK is the parent tripeptide Gly-His-Lys, originally isolated from human plasma by Loren Pickart (1973) as an activity that caused aged hepatocytes to synthesize proteins like younger tissue. It is DISTINCT from GHK-Cu, the 1:1 copper(II) complex tracked as a separate entry — but GHK binds copper readily in vivo, so in physiological environments the bare peptide rapidly associates with available Cu(II). Not FDA-approved for any indication; used in cosmetic and research contexts only.
Pricing for GHK
Live vendor pricing, normalized to $/mg so sizes compare fairly — fused with each seller's Merit trust score and latest independent COA purity. Prices refresh daily.
No COAs on file for GHK
No third-party tests indexed yet. Phase 2 will surface more vendor evidence as the dataset grows.
18 citations indexed for GHK
animal · 2026
The GHK-Cu delays aging in Caenorhabditis elegans via coordinated regulation of mitochondrial function and activation of DAF-16/SKN-1 pathways
Aging is a complex biological process characterized by progressive functional decline across tissues and increased susceptibility to age-related diseases, with oxidative stress being a key contributing factor.
animal · 2026
Middle-aged mice treated with GHK-Cu peptide administered intraperitoneally or intranasally show behavioral rescue but divergent hippocampal aging programs
Abstract Age-related cognitive decline (ARCD) is driven by conserved biological mechanisms of aging, yet no gerotherapeutic directly targets these processes in the brain.
animal · 2026
Glycyl-L-histidyl-L-lysine-Cu2<sup>+</sup> (GHK-Cu) Attenuates CuSO<sub>4</sub> or LPS induced-inflammation in Zebrafish larvae model
Inflammation serves as a basic defense mechanism against both internal and external threats, while the unresolved or excessive inflammation can lead to irreversible tissue damage.
Study · 2026
The Laccase-like Property of GHK-Cu and Its Applications in Colorimetric Sensing of Phenolic Compounds
Laccase plays an important role in the detection and degradation of phenolic compounds, but it is limited by its cost and stability. In this study, the laccase-like property of copper peptide (GHK-Cu) has been revealed.
Study · 2026
Evaluating neurochemical changes and associated locomotor activity in a double hit schizophrenia model
in-vitro · 2026
Microenvironment-responsive injectable dynamic hydrogel for sequential antioxidant and tissue regeneration therapy of radiation-induced skin injury
Radiotherapy is essential for cancer treatment, yet radiation-induced skin injury (RISI) remains a major clinical challenge due to reactive oxygen species (ROS) accumulation, metabolic dysregulation, and the limited efficacy of single-modality therapies in modulating the oxidative-inflammatory microenvironment.