Epithalon
Also known as: Epitalon (AEDG, synthetic analog of Epithalamin)
Epitalon is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) developed by Khavinson as an analog of the bovine pineal extract Epithalamin. It is a research-only bioregulator — not FDA-approved — investigated for claimed telomerase activation and circadian/melatonin effects, with evidence limited primarily to Khavinson-group studies.
Pricing for Epithalon
Live vendor pricing, normalized to $/mg so sizes compare fairly — fused with each seller's Merit trust score and latest independent COA purity. Prices refresh daily.
COAs for Epithalon
77 third-party tests across 20 vendors. Each card links to the full report.
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Epithalon
by OROS Research· batch OR-LPEPI10-526-B2
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Epithalon
by Crush Research· batch CRET-50-0212-1
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Epithalon
by BioLongevity Labs· batch 9-3-46146
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Epithalon
by Real Peptides· batch Orange Cap
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Epithalon
by Verified Peptides· batch cmp4wgbkb004jx7rxdpeilkwp
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Epithalon
by Verified Peptides· batch cmp4wgbn6004kx7rx72c6lhyu
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Epithalon
by Verified Peptides· batch cmp4wgbpl004lx7rxfa45zj6b
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Epithalon
by Peptide Plugs· batch 115-B-DK
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Epithalon
by Qihang Peptide· batch 4
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Epithalon
by OROS Research· batch OR-LPEPI10-326-B2
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Epithalon
by Glacier Aminos· batch EPI10GA-02
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Epithalon
by Amino Club· batch EPI0001
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Epithalon
by Ion Peptide· batch ET10-03102026
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Epithalon
by Crush Research· batch CR-ET40-0217-1
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Epithalon
by Ion Peptide· batch ET10-02232026
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Epithalon
by BioLongevity Labs· batch 9-3-46035
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Epithalon
by Ion Peptide· batch EP50-02032026
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Epithalon
by Ion Peptide· batch ET10-01272026
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Epithalon
by Peptide Supply Co.· batch cmpa6pv4g001o73rx1rxi2ek0
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Epithalon
by MedGe Peptides· batch EPI50A 11 14 25
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Epithalon
by MedGe Peptides· batch EPI50A T1 14 25
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Epithalon
by Cocer Peptides· batch CS-ep10-1228
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Epithalon
by Verified Peptides· batch EP01260710H
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Epithalon
by Simple Peptide· batch EPFIT12232025-J
13 citations indexed for Epithalon
review · 2026
Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions
Therapeutic peptides are emerging as promising adjuncts in the management of orthopaedic injuries, grounded in their ability to modulate molecular signaling networks central to cellular medicine.
review · 2026
Therapeutic peptides in gerontology: mechanisms and applications for healthy aging
Background Peptide therapeutics represent an emerging frontier in gerontological medicine, targeting fundamental hallmarks of aging including metabolic dysfunction, telomere attrition, tissue repair impairment, and hormonal decline.
meta-analysis · 2026
Efficacy and Safety of Melatonin in Migraine Prophylaxis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Background Migraine is a chronic, disabling brain disorder. Melatonin, a circadian regulator with anti-inflammatory and antinociceptive actions, has been proposed for migraine prevention. We evaluated the efficacy and safety of melatonin for prophylaxis.
review · 2025
Overview of Epitalon-Highly Bioactive Pineal Tetrapeptide with Promising Properties
Epitalon, also known as Epithalon or Epithalone, is a tetrapeptide, Ala-Glu-Asp-Gly (AEDG), which was synthesized based on the amino acids composition of Epithalamin, a bovine pineal gland extract, prior to its discovery in pineal gland polypeptide complex solution.
Study · 2025
Epitalon increases telomere length in human cell lines through telomerase upregulation or ALT activity
Epitalon, a naturally occurring tetrapeptide, is known for its anti-aging effects on mammalian cells. This happens through the induction of telomerase enzyme activity, resulting in the extension of telomere length. A strong link exists between telomere length and aging-related diseases.
review · 2024
[Peptidergic regulation of expression of cellular aging marker proteins in buccal epithelium.]
The review presents the results of long-term research conducted by the staff of the Saint-Petersburg Institute of Bioregulation and Gerontology, dedicated to the study of the biological activity of peptide bioregulators at all levels of a living organism's organization.