Bronchogen
Also known as: AEDL, Ala-Glu-Asp-Leu, T-33, lung peptide bioregulator
Synthetic short-chain tetrapeptide bioregulator (Ala-Glu-Asp-Leu, AEDL) from the Khavinson family of tissue-specific peptides, developed by Vladimir Khavinson and colleagues at the St. Petersburg Institute of Bioregulation and Gerontology and designed from amino-acid analysis of bronchial-mucosa peptide extracts. It is proposed to act epigenetically, penetrating cells and binding DNA to modulate tissue-specific gene expression and protein synthesis in bronchial epithelium and lung tissue. Evidence is almost entirely preclinical and from Russian-language sources; no controlled human clinical trials meeting international standards have been published. It is not FDA-approved or FDA-evaluated and is sold as a grey-market research compound.
Who's worth your money for Bronchogen
Every current seller, ranked by independent evidence — Merit Score, latest COA purity, and live $/mg (size-normalized). Prices refresh daily. Rankings are never paid.
Top Merit pick
Highest Merit Score (96) of 3 scored sellers
$69.97 · 20mg · 99.6% purity
Best value
Lowest $/mg among scored sellers
$79.00 · 20mg · 99.6% purity
Average price
$3.84/mg
Sellers
8
45-day trend
+11.8%
7 of 8 sellers have a current price· 1 stale hidden· 3 unverified hidden
Top Merit pick
🇺🇸 BioLongevity Labs96via Disclosed Labs · 23h ago
$3.50/mg -9% vs avg$69.97
20mg
- 🇺🇸 Ion Peptide95
✓ verified at source · 23h ago
$3.95/mg +2.8% vs avg$79.00
20mg
- 🇺🇸 EZ Peptides85
✓ verified at source · 23h ago
$5.80/mg +50.9% vs avg$58.00
10mg
no purity
Prices observed from public storefronts (last 24h), normalized to $/mg. "Evidence" is Merit's 0–100 Merit Score, derived only from observable verification evidence (methodology on /about); "Purity" is the latest independent COA. Some buy links are affiliate links — Merit may earn a commission at no extra cost to you, and where a vendor offers one, the code shown gets you a discount at their checkout. Affiliate status never affects price data, ranking, or the Merit Score (full policy on /disclosure). Research use only.
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About Bronchogen
CAS
—
Molecular formula
C18H30N4O9
Sequence
AEDL
Typical dose range
No validated human dose; vendor 'research' protocols commonly cite ~2-3 mg/day for 10-20 day courses (subcutaneous, unverified, research-only)
Half-life
Short circulating half-life (minutes); like other Khavinson bioregulators, biological effects are claimed to outlast plasma presence. Not formally characterized in humans.
Common research uses
Safety notes
Not FDA-approved or evaluated; no rigorous human safety data exist. Sold for research use only; human use is off-label and unvalidated. Not currently a WADA-listed substance.
Reconstitution
Sold as lyophilized powder; reconstitute with bacteriostatic water and refrigerate. Research-use only.
COAs for Bronchogen
8 third-party tests across 2 vendors. Each card links to the full report.
For
Bronchogen
by Kimera Chems· batch KC-BCH-BLK1
For
Bronchogen
by Ion Peptide· batch BN20-012026
For
Bronchogen
by BioLongevity Labs
For
Bronchogen
by BioLongevity Labs
For
Bronchogen
by BioLongevity Labs
For
Bronchogen
by Ion Peptide· batch BN20-012026
Purity not on file
For
Bronchogen
by BioLongevity Labs· batch 33-3-45952
Purity not on file
For
Bronchogen
by BioLongevity Labs
13 citations indexed for Bronchogen
review · 2021
Peptide Regulation of Gene Expression: A Systematic Review
Peptides are characterized by their wide range of biological activity: they regulate functions of the endocrine, nervous, and immune systems.
review · 2020
Peptides: Prospects for Use in the Treatment of COVID-19
There is a vast practice of using antimalarial drugs, RAS inhibitors, serine protease inhibitors, inhibitors of the RNA-dependent RNA polymerase of the virus and immunosuppressants for the treatment of the severe form of COVID-19, which often occurs in patients with chronic diseases and older persons.
Study · 2020
AEDG Peptide (Epitalon) Stimulates Gene Expression and Protein Synthesis during Neurogenesis: Possible Epigenetic Mechanism
It was shown that AEDG peptide (Ala-Glu-Asp-Gly, Epitalon) regulates the function of the pineal gland, the retina, and the brain. AEDG peptide increases longevity in animals and decreases experimental cancerogenesis.
Study · 2017
Short Exogenous Peptides Regulate Expression of CLE, KNOX1, and GRF Family Genes in Nicotiana tabacum
Exogenous short biologically active peptides epitalon (Ala-Glu-Asp-Gly), bronchogen (Ala-Glu-Asp-Leu), and vilon (Lys-Glu) at concentrations 10 -7 -10 -9 M significantly influence growth, development, and differentiation of tobacco (Nicotiana tabacum) callus cultures.
animal · 2017
[ANTIINFLAMMATORY AND REGENERATIVE EFFECT OF PEPTIDE THERAPY IN THE MODEL OF OBSTRUCTIVE LUNG PATHOLOGY]
The effect of the tetrapeptide bronchogen on the structural and functional state of the bronchial epithelium and inflammatory activity in the lungs was studied in the chronic obstructive pulmonary disease (COPD) model, created in rats by a 60-day intermittent exposure to nitrogen dioxide.
animal · 2015
Modulating Effect of Peptide Therapy on the Morphofunctional State of Bronchial Epithelium in Rats with Obstructive Lung Pathology
On the model of chronic obstructive pulmonary disease, the effect of therapy with low-molecular-weight peptides on restructuring and functional activity of bronchial epithelium for restoring the immune and barrier function of the lungs and prevention of inflammatory process progression was studied.
Research use only — not for human consumption and not approved by the FDA. Nothing here is medical advice.