Biotinoyl Tripeptide-1
Also known as: Biotinoyl Tripeptide, Biotin-GHK, Biotinyl-GHK, Biotinoyl-Gly-His-Lys
Cosmetic tripeptide consisting of the matrikine GHK (glycyl-L-histidyl-L-lysine) conjugated to biotin (vitamin H/B7) at the N-terminus. Marketed for hair and scalp use, where it is claimed to anchor the hair shaft in the follicle, prolong the anagen growth phase, and support dermal-papilla and follicular matrix activity; GHK itself is associated with copper binding and stimulation of extracellular-matrix components such as collagen and laminin. It is a topical cosmetic ingredient, not an FDA-approved drug; supporting evidence is mostly in-vitro and manufacturer-sponsored rather than from controlled clinical trials.
Who's worth your money for Biotinoyl Tripeptide-1
Every current seller, ranked by independent evidence — Merit Score, latest COA purity, and live $/mg (size-normalized). Prices refresh daily. Rankings are never paid.
Average price
—/mg
Sellers
1
45-day trend
building…
0 of 1 sellers have a current price
Prices observed from public storefronts (last 24h), normalized to $/mg. "Evidence" is Merit's 0–100 Merit Score, derived only from observable verification evidence (methodology on /about); "Purity" is the latest independent COA. Some buy links are affiliate links — Merit may earn a commission at no extra cost to you, and where a vendor offers one, the code shown gets you a discount at their checkout. Affiliate status never affects price data, ranking, or the Merit Score (full policy on /disclosure). Research use only.
Watch Biotinoyl Tripeptide-1
Get one email when the market actually moves — no newsletter, no noise.
About Biotinoyl Tripeptide-1
CAS
299157-54-3
Molecular formula
C24H38N8O6S
Sequence
GHK
Typical dose range
Topical only; used at low percentages of a dilute peptide trade solution in cosmetics (no systemic dosing established)
Half-life
Not characterized for systemic exposure; used as a topical cosmetic, not administered systemically
Common research uses
Safety notes
Topical cosmetic ingredient, not an FDA-approved drug. Efficacy claims (particularly for hair growth) are largely manufacturer- and in-vitro-derived; rigorous independent clinical data are limited. Not evaluated for systemic or injectable use. Not a WADA-listed substance.
Reconstitution
Water-soluble cosmetic raw material incorporated into topical formulations; not intended for injectable reconstitution.
COAs for Biotinoyl Tripeptide-1
2 third-party tests across 1 vendor. Each card links to the full report.
6 citations indexed for Biotinoyl Tripeptide-1
review · 2026
Overview of Short Peptides for Hair Loss
Hair serves essential functions, including mechanical sensing, head protection, and body temperature regulation, while also playing a significant role in human aesthetics.
Study · 2025
Optimizing neutralization strategies for microbial testing of non-sterile pharmaceutical finished products with challenging method suitability
Background Method suitability for microbial limit tests during microbiological quality control (QC) can be a complicated process that requires multiple steps of optimization and plays a central role in ensuring reliable QC results.
review · 2025
Topical Alternatives for Hair Loss: Beyond the Conventional
Topical hair growth supplements in the form of hair growth serums, oils, and shampoos have flooded the cosmeceutical market. The gullible masses are targeted with sponsored marketing gimmicks through social media platforms.
rct · 2025
Prostaglandin Analog Eyelash Serum and Ocular Surface Health: A Prospective Study
This prospective interventional study investigates the effects of a prostaglandin analog-based eyelash serum on ocular surface integrity, tear film stability, and eyelash growth over six weeks.
review · 2023
TFOS Lifestyle: Impact of cosmetics on the ocular surface
In this report the use of eye cosmetic products and procedures and how this represents a lifestyle challenge that may exacerbate or promote the development of ocular surface and adnexal disease is discussed.
rct · 2023
A Single-Group Study to Evaluate the Effects of an Eyelash Serum on Improving Eyelash Growth
This study will evaluate the efficacy of the DIME Beauty Eyelash Boost Serum in improving the growth of the eyelashes and their appearance in terms of length, fullness, and thickness. This study will last for 60 days. The study will be conducted as a single-arm trial in which all participants will use the test product.